To be or not to be a pro-T?
Details
Serval ID
serval:BIB_FF0ED1023CAD
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
To be or not to be a pro-T?
Journal
Current Opinion in Immunology
ISSN
0952-7915 (Print)
Publication state
Published
Issued date
04/2000
Volume
12
Number
2
Pages
159-65
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Apr
Research Support, Non-U.S. Gov't
Review --- Old month value: Apr
Abstract
Recent studies have begun to unravel some of the molecular pathways that appear to control the processes of T cell determination in the earliest thymocyte precursors. In addition, the analyses of mouse mutants with an entirely alymphoid thymus have shed light on the developmental relationship of pro-T cells and thymic dendritic cells, revealing that development of thymocytes and thymic dendritic cells can be dissociated.
Keywords
Animals
Calcium-Binding Proteins
Cell Differentiation
Cell Lineage
Cytokines/physiology
Dendritic Cells/cytology
*Gene Expression Regulation, Developmental
Helix-Loop-Helix Motifs
*Hematopoiesis/genetics
Hematopoietic Cell Growth Factors/physiology
Hematopoietic Stem Cells/*cytology
Humans
Inhibitor of Differentiation Protein 1
Intercellular Signaling Peptides and Proteins
Membrane Proteins/physiology
Mice
Radiation Chimera
Receptors, Cytokine/physiology
Receptors, Notch
*Repressor Proteins
Signal Transduction
T-Lymphocyte Subsets/*cytology
Thymus Gland/cytology
Transcription Factors/classification/physiology
Transcription, Genetic
Pubmed
Web of science
Create date
28/01/2008 11:39
Last modification date
20/08/2019 16:29