Nephrotic syndrome after liver transplantation in a patient with hepatitis C virus-associated glomerulonephritis
Details
Serval ID
serval:BIB_FEEF9CE56229
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Nephrotic syndrome after liver transplantation in a patient with hepatitis C virus-associated glomerulonephritis
Journal
Transplantation
ISSN
0041-1337
Publication state
Published
Issued date
10/1997
Peer-reviewed
Oui
Volume
64
Number
7
Pages
1073-6
Notes
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Oct 15
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Oct 15
Abstract
In recent years, hepatitis C virus infection has been reported to be typically associated with membranoproliferative glomerulonephritis and less frequently with membranous nephropathy. Treatment of hepatitis C with interferon-alpha can reduce viremia and improve renal disease. After liver transplantation for hepatitis C virus-associated liver failure, standard immunosuppressive protocols result in a significant increase in hepatitis C viremia. In this report we describe a patient with end-stage liver disease and biopsy-proven hepatitis C-associated glomerulonephritis who underwent liver transplantation. Within 1 month after transplantation, he developed a severe nephrotic syndrome that paralleled a marked increase in viremia. We discuss the possible pathogenic relationship between hepatitis C virus infection and the nephrotic syndrome that followed liver transplantation.
Keywords
Angiotensin-Converting Enzyme Inhibitors/therapeutic use
Creatinine/blood
Enalapril/therapeutic use
Female
Glomerulonephritis/*complications/virology
Hepacivirus/isolation & purification
Hepatitis C/*complications/surgery/therapy
Humans
Kidney Transplantation
*Liver Transplantation/physiology
Middle Aged
Nephrotic Syndrome/*etiology
*Postoperative Complications
Proteinuria
RNA, Viral/blood
Reoperation
Time Factors
Viremia/*complications
Pubmed
Web of science
Create date
29/01/2008 13:53
Last modification date
20/08/2019 16:29