Acute aphasia after right hemisphere stroke

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Serval ID
serval:BIB_FECFB9A34057
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Acute aphasia after right hemisphere stroke
Journal
Journal of Neurology
Author(s)
Dewarrat G. M., Annoni J. M., Fornari E., Carota A., Bogousslavsky J., Maeder P.
ISSN
1432-1459
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Pages
1461-1467
Language
english
Abstract
Right hemispheric stroke aphasia (RHSA) rarely occurs in right- or left-handed patients with their language representation in right hemisphere (RH). For right-handers, the term crossed aphasia is used. Single cases, multiple cases reports, and reviews suggest more variable anatomo-clinical correlations. We included retrospectively from our stroke data bank 16 patients (right- and left-handed, and ambidextrous) with aphasia after a single first-ever ischemic RH stroke. A control group was composed of 25 successive patients with left hemispheric stroke and aphasia (LHSA). For each patient, we analyzed four modalities of language (spontaneous fluency, naming, repetition, and comprehension) and recorded eventual impairment: (1) on admission (hyperacute) and (2) between day 3 and 14 (acute). Lesion volume and location as measured on computed tomography (CT) and magnetic resonance imaging (MRI) were transformed into Talairach stereotaxic space. Nonparametric statistics were used to compare impaired/nonimpaired patients. Comprehension and repetition were less frequently impaired after RHSA (respectively, 56% and 50%) than after LHSA (respectively, 84% and 80%, P = 0.05 and 0.04) only at hyperacute phase. Among RHSA, fewer left-handers/ambidextrous than right-handers had comprehension disorders at second evaluation (P = 0.013). Mean infarct size was similar in RHSA and LHSA with less posterior RHSA lesions (caudal to the posterior commissure). Comprehension and repetition impairments were more often associated with anterior lesions in RHSA (Fisher's exact test, P < 0.05). Despite the small size of the cohort, our findings suggest increased atypical anatomo-functional correlations of RH language representation, particularly in non-right-handed patients.
Pubmed
Web of science
Open Access
Yes
Create date
14/05/2009 14:48
Last modification date
01/10/2019 7:20
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