Macrophage migration inhibitory factor reduces the growth of virulent Mycobacterium tuberculosis in human macrophages
Details
Serval ID
serval:BIB_FEA7D10E27FF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Macrophage migration inhibitory factor reduces the growth of virulent Mycobacterium tuberculosis in human macrophages
Journal
Infection and Immunity
ISSN
0019-9567 (Print)
Publication state
Published
Issued date
06/2005
Volume
73
Number
6
Pages
3783-6
Notes
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jun
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jun
Abstract
Macrophage migration inhibitory factor (MIF) is a key mediator of the innate immune system and plays a crucial role in the host response to bacterial infections. Its role in immunity to intracellular pathogens has not been well studied. Here, we show that MIF released by infected human macrophages inhibits the growth of virulent Mycobacterium tuberculosis.
Keywords
Humans
Macrophage Migration-Inhibitory Factors/*physiology
Macrophages/*immunology/microbiology
Mycobacterium tuberculosis/growth & development/*immunology
Virulence
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2008 14:28
Last modification date
20/08/2019 17:29