The importance of mucosal immunity in defense against epithelial cancers

Details

Serval ID
serval:BIB_FDBC2C61C0DB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The importance of mucosal immunity in defense against epithelial cancers
Journal
Current Opinion in Immunology
Author(s)
Revaz  V., Nardelli-Haefliger  D.
ISSN
0952-7915 (Print)
Publication state
Published
Issued date
04/2005
Volume
17
Number
2
Pages
175-9
Notes
Journal Article
Review --- Old month value: Apr
Abstract
Many cancers arise in epithelial mucosa. These mucosal surfaces are characterized by the induction of divergent immune responses, as they are both the main portal of entry for pathogens and a large niche of commensal bacteria and tolerized antigens. In addition, mucosa located in different anatomical sites harbor distinct typical features. Exploiting the different requirements for inducing an effective immune response at mucosal sites might help to define new immunotherapeutic approaches against epithelial cancers, at least in the case of differentiated tumors that have retained their mucosal characteristics.
Keywords
Cancer Vaccines Colorectal Neoplasms/immunology/therapy Genitalia/immunology Humans Immunity, Mucosal/*immunology Immunotherapy Intestines/immunology Neoplasms, Glandular and Epithelial/*immunology/prevention & control/therapy Papillomaviridae/immunology
Pubmed
Web of science
Create date
25/01/2008 15:35
Last modification date
20/08/2019 17:28
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