Myocardial perfusion imaging by cardiac magnetic resonance.

Details

Serval ID
serval:BIB_FDAF5B95230F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Myocardial perfusion imaging by cardiac magnetic resonance.
Journal
Journal of Nuclear Cardiology
Author(s)
Schwitter J.
ISSN
1532-6551 (Electronic)
ISSN-L
1071-3581
Publication state
Published
Issued date
2006
Volume
13
Number
6
Pages
841-854
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
Cardiovascular magnetic resonance (CMR) has been shown to provide high quality data on cardiac and valvular function, perfusion, viability, blood flow, and potentially, on cardiac metabolism as well. Several of these CMR applications (eg, function and viability assessment) matured during the past years and are now established components of a cardiac workup. Perfusion-CMR is close to this status and is already a major contributor to cardiac examinations in a growing number of expert centers. Large multicenter perfusion-CMR trials comparing the diagnostic performance of CMR with other techniques were recently reported yielding areas under the receiver-operator-characteristics curve as a high as 0.85 for coronary artery disease detection (MR-IMPACT). Anticipating a growing role for perfusion-CMR in cardiology in the near future, this article discusses the principles of perfusion-CMR and its integration into the workup of patient with coronary artery disease (CAD). In addition to a functional study, this integration is mainly composed of a perfusion-CMR part, followed by a viability assessment by late enhancement CMR techniques. The principal characteristics of these CMR techniques are compared with those of single photon emission computed tomography (SPECT) and positron emission tomography (PET). After introduction into principles and techniques of perfusion-CMR, some open questions in perfusion-CMR and challenges for the future are addressed. Finally, newer CMR applications are shortly mentioned utilizing hyperpolarized carbon-13 compounds in experimental models for quantification of myocardial perfusion and for real-time assessment of metabolic pathways in postischemic myocardium.
Keywords
Clinical Trials as Topic, Coronary Artery Disease/complications, Coronary Artery Disease/diagnosis, Humans, Image Enhancement/methods, Image Interpretation, Computer-Assisted/methods, Magnetic Resonance Imaging/methods, Myocardial Ischemia/complications, Myocardial Ischemia/diagnosis, Technology Assessment, Biomedical, Ventricular Dysfunction, Left/diagnosis, Ventricular Dysfunction, Left/etiology
Pubmed
Web of science
Create date
07/09/2011 19:37
Last modification date
20/08/2019 16:28
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