Traitements actuels du lymphome folliculaire [Current treatment of follicular lymphoma]

Details

Serval ID
serval:BIB_FD7BC57F2F1D
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Traitements actuels du lymphome folliculaire [Current treatment of follicular lymphoma]
Journal
Revue Médicale Suisse
Author(s)
Bonnet C., Beguin Y., Deprijck B., de Leval L., Fillet G.
ISSN
1660-9379[print], 1660-9379[linking]
Publication state
Published
Issued date
2009
Volume
5
Number
214
Pages
1663-1667
Language
french
Abstract
After diffuse large B-cell lymphoma, follicular lymphoma is the most frequent non-Hodgkin's lymphoma. It remains incurable, except for localized diseases. Advanced disease has to be treated only in the presence of clinical and/or biology aggressiveness. These patients should be treated by rituximab (Mab-Thera) associated to polychemotherapy comprising cyclophosphamide, vincristine and prednisone. After this therapy, the benefit of rituximab in maintenance has to be confirmed. Autologous stem cell transplantation is now reserved for young patients in first relapse. Allogenic stem cell transplantation is also an interesting option. The other therapeutic options comprise radio-immunotherapy with 90Y ibritumomab tiuxetan (Zevalin) and bortezomib (Velcade).
Keywords
Antibodies, Monoclonal/administration & dosage, Antibodies, Monoclonal/therapeutic use, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Boronic Acids/administration & dosage, Chemotherapy, Adjuvant, Cyclophosphamide/administration & dosage, Hematopoietic Stem Cell Transplantation, Humans, Lymphoma, Follicular/drug therapy, Lymphoma, Follicular/radiotherapy, Prednisone/administration & dosage, Prognosis, Pyrazines/administration & dosage, Radioimmunotherapy, Radiotherapy, Adjuvant, Risk Factors, Transplantation, Autologous, Transplantation, Homologous, Treatment Outcome, Vincristine/administration & dosage
Pubmed
Create date
22/10/2010 13:33
Last modification date
20/08/2019 16:28
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