Endometrium preparation with exogenous estradiol and progesterone for the transfer of cryopreserved blastocysts

Details

Serval ID
serval:BIB_FD144B1725C1
Type
Article: article from journal or magazin.
Collection
Publications
Title
Endometrium preparation with exogenous estradiol and progesterone for the transfer of cryopreserved blastocysts
Journal
Fertility and Sterility
Author(s)
Lelaidier  C., de Ziegler  D., Freitas  S., Olivennes  F., Hazout  A., Frydman  R.
ISSN
0015-0282
Publication state
Published
Issued date
04/1995
Peer-reviewed
Oui
Volume
63
Number
4
Pages
919-21
Notes
Journal Article --- Old month value: Apr
Abstract
OBJECTIVE: To determine the implantation rates of cryopreserved blastocysts using controlled E2 and P replacement cycles in women with functioning ovaries. DESIGN: Retrospective clinical study. SETTING: University teaching hospital. PATIENTS: Infertile women with cryopreserved blastocysts obtained from previous IVF attempts. INTERVENTIONS: Exogenous E2 was administered orally from cycle day 1 and P was started transvaginally from day 15. Blastocysts were transferred on the 5th day of endometrial exposure to P (day 19). MAIN OUTCOME MEASURES: Blastocyst implantation rate and pregnancy rate (PR). RESULTS: Ninety-eight percent of blastocysts survived thawing: 67 were transferred in 42 women. Eight pregnancies occurred giving a PR of 19% per ET and 11.9% per blastocyst. CONCLUSION: The high PR observed after transferring blastocysts on the 5th day of endometrial exposure to P in controlled E2 and P replacement cycles speaks for a forward slide of the window of transfer in case of blastocysts.
Keywords
Adult Blastocyst/*physiology *Cryopreservation Embryo Implantation *Embryo Transfer Endometrium/*drug effects/physiology Estradiol/*therapeutic use Female Humans Pregnancy Progesterone/*therapeutic use Retrospective Studies
Pubmed
Web of science
Create date
28/02/2008 11:37
Last modification date
20/08/2019 16:28
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