UniPathway: a resource for the exploration and annotation of metabolic pathways.

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Serval ID
serval:BIB_FC8A2825CAF8
Type
Article: article from journal or magazin.
Collection
Publications
Title
UniPathway: a resource for the exploration and annotation of metabolic pathways.
Journal
Nucleic Acids Research
Author(s)
Morgat A., Coissac E., Coudert E., Axelsen K.B., Keller G., Bairoch A., Bridge A., Bougueleret L., Xenarios I., Viari A.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Publication state
Published
Issued date
2012
Volume
40
Number
Database issue
Pages
D761-D769
Language
english
Abstract
UniPathway (http://www.unipathway.org) is a fully manually curated resource for the representation and annotation of metabolic pathways. UniPathway provides explicit representations of enzyme-catalyzed and spontaneous chemical reactions, as well as a hierarchical representation of metabolic pathways. This hierarchy uses linear subpathways as the basic building block for the assembly of larger and more complex pathways, including species-specific pathway variants. All of the pathway data in UniPathway has been extensively cross-linked to existing pathway resources such as KEGG and MetaCyc, as well as sequence resources such as the UniProt KnowledgeBase (UniProtKB), for which UniPathway provides a controlled vocabulary for pathway annotation. We introduce here the basic concepts underlying the UniPathway resource, with the aim of allowing users to fully exploit the information provided by UniPathway.
Keywords
Databases, Factual, Databases, Protein, Enzymes/metabolism, Lysine/biosynthesis, Metabolic Networks and Pathways, Molecular Sequence Annotation
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2012 9:39
Last modification date
20/08/2019 16:27
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