New developments in laboratory monitoring of HIV-1 infection.

Details

Serval ID
serval:BIB_FC7591D9960C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
New developments in laboratory monitoring of HIV-1 infection.
Journal
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Author(s)
Telenti A.
ISSN
1198-743X
Publication state
Published
Issued date
2002
Peer-reviewed
Oui
Volume
8
Number
3
Pages
137-43
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review - Publication Status: ppublish
Abstract
The laboratory tests currently available to the clinician for day-to-day management of HIV infection are generally limited to the measurement of the viral load and of the CD4 cell count. More recently, analysis of drug resistance and of plasma drug levels have been added to the monitoring armamentarium. There are, however, numerous other techniques currently available to researchers that may in the future be incorporated into clinical routine. These include the analysis of human and viral genetic determinants of disease evolution, detailed analyses of immune recovery and reserve, pharmacogenetic determinants of treatment response, and toxicity. These approaches may in the future provide highly individualized disease management.
Keywords
Anti-HIV Agents, Clinical Laboratory Techniques, Disease Progression, Drug Monitoring, Drug Resistance, Viral, Genetic Predisposition to Disease, HIV Infections, HIV-1, Humans, Pharmacogenetics, Virus Replication
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2008 15:46
Last modification date
20/08/2019 17:27
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