Perspectives de recherche sur la vaccination antipaludique [Research on malaria vaccine].

Details

Serval ID
serval:BIB_FBCB355EFAE5
Type
Article: article from journal or magazin.
Collection
Publications
Title
Perspectives de recherche sur la vaccination antipaludique [Research on malaria vaccine].
Journal
Dakar Médical
Author(s)
Dieye A., Launois P., Sarthou J.L.
ISSN
0049-1101 (Print)
ISSN-L
0049-1101
Publication state
Published
Issued date
1990
Volume
35
Number
2
Pages
268-275
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Malaria is an important public health problem in developing countries. The production of a good vaccine needs a better knowledge of different mechanisms which control the immune system. Results from donors show a higher frequency of antigens HLA: A2, B35, CW4, CW6, DRW52, DQW1 and DQW3. The lymphoproliferation in vitro of mononuclear cells, T cells and CD4+ and CD8+ subsets T cells with merozoite extracts is not so clear to establish a correlation between HLA phenotypes and T cells response.
Keywords
Adult, Animals, Antigens, Protozoan/immunology, Female, Genetic Predisposition to Disease, HLA Antigens/analysis, Humans, Immunity, Cellular, Leukocytes, Mononuclear/immunology, Lymphocyte Activation, Malaria, Falciparum/prevention & control, Male, Middle Aged, Phenotype, Plasmodium falciparum/growth & development, Plasmodium falciparum/immunology, Protozoan Proteins/immunology, Protozoan Vaccines, T-Lymphocyte Subsets/immunology, Vaccines
Pubmed
Create date
28/01/2008 11:06
Last modification date
20/08/2019 16:26
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