T-Flux implant versus Healon GV in deep sclerectomy.

Details

Serval ID
serval:BIB_FB89F9DBD1AB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
T-Flux implant versus Healon GV in deep sclerectomy.
Journal
Journal of glaucoma
Author(s)
Ravinet E., Bovey E., Mermoud A.
ISSN
1057-0829
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
13
Number
1
Pages
46-50
Language
english
Notes
Publication types: Clinical Trial ; Journal Article ; Randomized Controlled Trial - Publication Status: ppublish
Abstract
PURPOSE: To compare the efficacy and safety of T-Flux implant versus Healon GV in deep sclerectomy. METHODS: Randomized prospective trial of 23 eyes of 20 patients with medically uncontrolled open angle glaucoma over a period of 24 months, who underwent deep sclerectomy with either Healon GV or T-Flux implant. RESULTS: Mean postoperative intraocular pressure was 13.2 +/- 3.0 mm Hg with T-Flux implant (group 1) and 12.2 +/- 3.5 mm Hg with Healon GV (group 2), with a pressure reduction of 53.0% in group 1 (13.2 mm Hg vs. 28.1 mm Hg) and of 48.1% in group 2 (12.2 mm Hg vs. 23.5 mm Hg). Qualified and complete successes were 100% and 95.4% respectively. Pressures equal to or less than 15 mm Hg were 81.8% in group 1 and 90.9% in group 2 with or without treatment, and 63.6% in group 1 and 81.8% in group 2 without treatment. The number of glaucoma treatments dropped from 2.5 +/- 0.9 to 0.4 +/- 0.7 in group 1 and from 2.2 +/- 1.0 to 0.2 +/- 0.4 in group 2. The goniopuncture rate was 63.6% in group 1 and 36.4% in group 2, with a mean pressure drop of 6.1 +/- 3.9 mm Hg and 3.25 +/- 1.2 mm Hg respectively. Overall, slit-lamp diagnosed surgery-related complications included positive Seidel (13.6%), hyphaema (22.7%), choroidal detachment, and iris incarceration (4.5% each). At 2 years, ultrasound biomicroscopy showed mainly low reflective (40.1%) and flattened (36.4%) blebs. Principally latter ones were associated with the need for adjunctive treatment. A hypoechoic area in the suprachoroidal space was seen in at least 59.1% of eyes at 2 years and was not associated with lower intraocular pressure. CONCLUSION: Deep sclerectomy is an effective and safe surgery. However, longer follow up and larger study groups are required to assess the additional benefit of nonabsorbable implants.
Keywords
Aged, Antimetabolites, Blister, Cornea, Female, Filtering Surgery, Glaucoma, Open-Angle, Humans, Hyaluronic Acid, Intraocular Pressure, Male, Middle Aged, Pilot Projects, Prostheses and Implants, Punctures, Sclera, Sclerostomy
Pubmed
Web of science
Create date
28/02/2008 13:01
Last modification date
20/08/2019 16:26
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