Performance characteristics of the new Eurosets magnetically suspended centrifugal pump.

Details

Serval ID
serval:BIB_FB3779406020
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Performance characteristics of the new Eurosets magnetically suspended centrifugal pump.
Journal
Perfusion
Author(s)
Berdajs D., von Segesser L.K., Maisano F., Milano G., Ferrari E.
ISSN
1477-111X (Electronic)
ISSN-L
0267-6591
Publication state
Published
Issued date
03/2021
Peer-reviewed
Oui
Volume
36
Number
2
Pages
183-189
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The aim was to evaluate the performance of a newly developed magnetically suspended centrifugal pump head intended for use as a ventricular assistance device with a newly developed extracorporeal membrane oxygenator setup.
In an experimental setup, an extracorporeal membrane oxygenator circuit was established in three calves with a mean weight of 68.2 ± 2.0 kg. A magnetically levitated centrifugal pump was tested, along with a newly designed extracorporeal membrane oxygenator console, at three different flow ranges: (a) 0.0 to 5.2 L/min, (b) 0.0 to 7.1 L/min, and (c) 0.0 to 6.0 L/min. For each setup, the animals were supported by a circuit for 6 h. Blood samples were collected just before caridiopulmonary bypass (CPB) after 10 min on bypass and after 1, 2, 5, and 6 h of perfusion for hemolysis determination and biochemical tests. Values were recorded for blood pressure, mean flow, and pump rotational speed. Analysis of variance was used for repeated measurements.
Mean pump flows achieved during the three 6 h pump runs for the three pump heads studied were as follows: (a) flow range 0.0 to 5.2 L/min, 3.6 ± 1.5 L/min, (b) flow range 0.0 to 7.1 L/min, 4.9 ± 1.3 L/min, and (c) flow range 0.0 to 6.0 L/min, 3.8 ± 1.5 L/min. Blood trauma, evaluated by plasma hemoglobin and lactate dehydrogenase levels, did not help in detecting any significant hemolysis. Thrombocytes and white blood cell count profiles showed no significant differences between the groups at the end of the 6 h perfusion. At the end of testing, no clot deposition was found in the oxygenator, and there was no evidence of peripheral emboli.
The results suggest that the newly developed magnetically suspended centrifugal pump head provides satisfactory hydrodynamic performance in an acute perfusion scenario without increasing hemolysis.
Keywords
ECLS, ECMO, centrifugal pump, hemolysis, hydrodynamic performance
Pubmed
Web of science
Create date
03/07/2020 19:42
Last modification date
05/05/2021 6:36
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