Study protocol for the OligoMetastatic Esophagogastric Cancer (OMEC) project: A multidisciplinary European consensus project on the definition and treatment for oligometastatic esophagogastric cancer.

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_F9C8EA647E0C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Study protocol for the OligoMetastatic Esophagogastric Cancer (OMEC) project: A multidisciplinary European consensus project on the definition and treatment for oligometastatic esophagogastric cancer.
Journal
European journal of surgical oncology
Author(s)
Kroese T.E., van Rossum PSN, Nilsson M., Lordick F., Smyth E.C., Rosati R., Nafteux P., D'Ugo D., Chaudry M.A., Polkowkski W., Roviello F., Gockel I., Kolodziejczyk P., Haustermans K., Guckenberger M., Nordsmark M., Hawkins M.A., Cervantes A., Fleitas T., van Cutsem E., Moehler M., Wagner A.D., van Laarhoven HWM, van Hillegersberg R.
Working group(s)
OMEC-working group (Supplementary File 1)
ISSN
1532-2157 (Electronic)
ISSN-L
0748-7983
Publication state
Published
Issued date
01/2023
Peer-reviewed
Oui
Volume
49
Number
1
Pages
21-28
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
A uniform definition and treatment for oligometastatic esophagogastric cancer is currently lacking. However, a comprehensive definition of oligometastatic esophagogastric cancer is necessary to initiate studies on local treatment strategies (e.g. metastasectomy or stereotactic radiotherapy) and new systemic therapy agents in this group of patients. For this purpose, the OligoMetastatic Esophagogastric Cancer (OMEC) project was established. The OMEC-project aims to develop a multidisciplinary European consensus statement on the definition, diagnosis, and treatment for oligometastatic esophagogastric cancer and provide a framework for prospective studies to improve outcomes of these patients.
The OMEC-project consists of five studies, including 1) a systematic review on definitions and outcomes of oligometastatic esophagogastric cancer; 2) real-life clinical scenario discussions in multidisciplinary expert teams to determine the variation in the definition and treatment strategies; 3) Delphi consensus process through a starting meeting, two Delphi questionnaire rounds, and a consensus meeting; 4) publication of a multidisciplinary European consensus statement; and 5) a prospective clinical trial in patients with oligometastatic esophagogastric cancer.
The OMEC project aims to establish a multidisciplinary European consensus statement for oligometastatic esophagogastric cancer and aims to initiate a prospective clinical trial to improve outcomes for these patients. Recommendations from OMEC can be used to update the relevant guidelines on treatment for patients with (oligometastatic) esophagogastric cancer.
Keywords
Humans, Esophageal Neoplasms/diagnosis, Esophageal Neoplasms/therapy, Prospective Studies, Stomach Neoplasms/diagnosis, Stomach Neoplasms/therapy, Systematic Reviews as Topic, Clinical Trials as Topic, Esophageal cancer, Gastric cancer, Metastasectomy, Oligometastasis, Radiotherapy
Pubmed
Web of science
Open Access
Yes
Create date
11/10/2022 12:28
Last modification date
16/11/2023 7:24
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