DNA fingerprinting from tissues after variable postmortem periods.

Details

Serval ID
serval:BIB_F903EFF0586D
Type
Article: article from journal or magazin.
Collection
Publications
Title
DNA fingerprinting from tissues after variable postmortem periods.
Journal
Journal of Forensic Sciences
Author(s)
Ludes B., Pfitzinger H., Mangin P.
ISSN
0022-1198[print], 0022-1198[linking]
Publication state
Published
Issued date
1993
Volume
38
Number
3
Pages
686-690
Language
english
Abstract
DNA typing is a useful tool in forensic cases for determining the identity of remains of humans who have been dead for various periods of time. DNA fingerprinting can be achieved only if high molecular weight DNA (HMWDNA) is extracted from the tissue samples of the bodies even after a long postmortem delay. Analyses were performed on various tissues collected during forensic autopsies of 24 bodies known postmortem ages. Tissues such as blood and kidney were found to be unsuitable for DNA fingerprinting because of a rapid degradation of the DNA after a period of one week. HMWDNA could be successfully extracted from brain cortex regardless of postmortem age.
Keywords
DNA Fingerprinting, Forensic Medicine/methods, Humans, Postmortem Changes
Pubmed
Create date
18/10/2010 15:27
Last modification date
03/03/2018 22:53
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