Factors Confounding the Athlete Biological Passport: A Systematic Narrative Review.

Details

Serval ID
serval:BIB_F771DEAA7F81
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Factors Confounding the Athlete Biological Passport: A Systematic Narrative Review.
Journal
Sports medicine - open
Author(s)
Krumm B., Faiss R.
ISSN
2199-1170 (Print)
ISSN-L
2198-9761
Publication state
Published
Issued date
15/09/2021
Peer-reviewed
Oui
Volume
7
Number
1
Pages
65
Language
english
Notes
Publication types: Systematic Review
Publication Status: epublish
Abstract
Through longitudinal, individual and adaptive monitoring of blood biomarkers, the haematological module of the athlete biological passport (ABP) has become a valuable tool in anti-doping efforts. The composition of blood as a vector of oxygen in the human body varies in athletes with the influence of multiple intrinsic (genetic) or extrinsic (training or environmental conditions) factors. In this context, it is fundamental to establish a comprehensive understanding of the various causes that may affect blood variables and thereby alter a fair interpretation of ABP profiles.
This literature review described the potential factors confounding the ABP to outline influencing factors altering haematological profiles acutely or chronically.
Our investigation confirmed that natural variations in ABP variables appear relatively small, likely-at least in part-because of strong human homeostasis. Furthermore, the significant effects on haematological variations of environmental conditions (e.g. exposure to heat or hypoxia) remain debatable. The current ABP paradigm seems rather robust in view of the existing literature that aims to delineate adaptive individual limits. Nevertheless, its objective sensitivity may be further improved.
This narrative review contributes to disentangling the numerous confounding factors of the ABP to gather the available scientific evidence and help interpret individual athlete profiles.
Keywords
Athlete biological passport, Blood passport, Haematological variables
Pubmed
Web of science
Open Access
Yes
Create date
21/09/2021 10:46
Last modification date
12/03/2022 7:29
Usage data