EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data.

Details

Ressource 1Download: serval:BIB_F4564B3C6DBD.P001 (145.79 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_F4564B3C6DBD
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data.
Journal
Bioinformatics (oxford, England)
Author(s)
Winkler T.W., Kutalik Z., Gorski M., Lottaz C., Kronenberg F., Heid I.M.
ISSN
1367-4811 (Electronic)
ISSN-L
1367-4803
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
31
Number
2
Pages
259-261
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
The R package EasyStrata facilitates the evaluation and visualization of stratified genome-wide association meta-analyses (GWAMAs) results. It provides (i) statistical methods to test and account for between-strata difference as a means to tackle gene-strata interaction effects and (ii) extended graphical features tailored for stratified GWAMA results. The software provides further features also suitable for general GWAMAs including functions to annotate, exclude or highlight specific loci in plots or to extract independent subsets of loci from genome-wide datasets. It is freely available and includes a user-friendly scripting interface that simplifies data handling and allows for combining statistical and graphical functions in a flexible fashion.
AVAILABILITY: EasyStrata is available for free (under the GNU General Public License v3) from our Web site www.genepi-regensburg.de/easystrata and from the CRAN R package repository cran.r-project.org/web/packages/EasyStrata/.
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Pubmed
Web of science
Open Access
Yes
Create date
31/10/2014 9:48
Last modification date
25/09/2019 7:11
Usage data