Benzodiazepine use among older adults with schizophrenia spectrum disorder: prevalence and associated factors in a multicenter study

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State: Public
Version: Author's accepted manuscript
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Serval ID
serval:BIB_F4177ECFFD29
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Benzodiazepine use among older adults with schizophrenia spectrum disorder: prevalence and associated factors in a multicenter study
Journal
International Psychogeriatrics
Author(s)
Schuster Jean-Pierre, Hoertel Nicolas, von Gunten Armin, Seigneurie Anne-Sophie, Limosin Frédéric
ISSN
1741-203X (Electronic)
ISSN-L
1041-6102
Publication state
Published
Issued date
04/2020
Peer-reviewed
Oui
Volume
32
Number
4
Pages
441-451
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Data on psychotropic medications of older patients with schizophrenia spectrum disorder are scarce. Specifically, information about the use of benzodiazepines among older patients with schizophrenia spectrum disorder is very limited. Because benzodiazepine use in older patients has been associated with many disabling side effects, its use in actual practice must be described and questioned. This study aimed at exploring the prevalence of benzodiazepine use and the clinical factors associated with such use among older patients with schizophrenia spectrum disorder.
Data from the Cohort of individuals with Schizophrenia Aged 55 years or more (CSA) were used to examine the prevalence of benzodiazepine use among older patients with schizophrenia spectrum disorder. Demographic and clinical characteristics associated with benzodiazepine prescription were also explored.
The prevalence of benzodiazepine use was 29.8% of older patients with schizophrenia spectrum disorder. These patients were significantly more likely to have medical comorbidities, cognitive and social functioning impairments, to report a lifetime history of suicide attempt, to be institutionalized, and to have been hospitalized in a psychiatric service in the past year compared to those without a benzodiazepine prescription (all p<0.05). There were no between-group differences in schizophrenia severity and psychiatric comorbidity.
Although it can be hypothesized that benzodiazepine prescription is part of a short-term therapeutic strategy toward patients with more severe trouble or comorbid disorders, our results suggest a strong link between benzodiazepine prescription and a particularly vulnerable subpopulation of older patients with schizophrenia spectrum disorder.
Keywords
Gerontology, Clinical Psychology, Geriatrics and Gerontology, Psychiatry and Mental health
Pubmed
Web of science
Create date
07/05/2019 15:37
Last modification date
04/05/2020 6:05
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