Pathogenesis and potential strategies for prevention and treatment of septic shock: an update

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Ressource 1Download: serval:BIB_F414EDC0843D.P001 (1311.23 [Ko])
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It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_F414EDC0843D
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Pathogenesis and potential strategies for prevention and treatment of septic shock: an update
Journal
Clinical Infectious Diseases
Author(s)
Glauser  M. P., Heumann  D., Baumgartner  J. D., Cohen  J.
ISSN
1058-4838
Publication state
Published
Issued date
02/1994
Peer-reviewed
Oui
Volume
18 Suppl 2
Pages
S205-16
Language
english
Notes
Journal Article
Review --- Old month value: Feb
licence nationale
Abstract
Septic shock is mediated by complex interactions of cells, cytokines, and humoral pathways. Clinical therapeutic strategies aimed at inhibiting selected pathways have been efficacious in subsets of patients. Experimental studies focusing on the activities of single cytokines have contributed to the understanding of the complex pathophysiology of septic shock. More precise delineation of the roles of each mechanism contributing to pathogenesis will permit the identification of subsets of patients who might benefit from particular therapeutic strategies and will guide the development of additional approaches to prevention and treatment.
Keywords
Cytokines/immunology Endotoxins/immunology Gram-Negative Bacterial Infections/*immunology Humans Shock, Septic/*etiology/*therapy
Pubmed
Web of science
Open Access
Yes
Create date
19/01/2008 19:12
Last modification date
01/10/2019 7:20
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