Circulating Biomarkers for Alzheimer's Disease: Unlocking the Diagnostic Potential in Low- and Middle-Income Countries, Focusing on Africa.

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_F1904186A629
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Circulating Biomarkers for Alzheimer's Disease: Unlocking the Diagnostic Potential in Low- and Middle-Income Countries, Focusing on Africa.
Journal
Neuro-degenerative diseases
Author(s)
Nwamekang Belinga L., Espourteille J., Wepnyu Njamnshi Y., Zafack Zeukang A., Rouaud O., Kongnyu Njamnshi A., Allali G., Richetin K.
ISSN
1660-2862 (Electronic)
ISSN-L
1660-2854
Publication state
Published
Issued date
29/03/2024
Peer-reviewed
Oui
Pages
1-15
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: aheadofprint
Abstract
Alzheimer's disease (AD) is emerging as a significant public health challenge in Africa, with predictions indicating a tripling in incidence by 2050. The diagnosis of AD on the African continent is notably difficult, leading to late detection that severely limits treatment options and significantly impacts the quality of life for patients and their families.
This review focuses on the potential of high-sensitivity specific blood biomarkers as promising tools for improving AD diagnosis and management globally, particularly in Africa. These advances are particularly pertinent in the continent, where access to medical and technical resources is often limited.
Identifying precise, sensitive, and specific blood biomarkers could contribute to the biological characterization and management of AD in Africa. Such advances promise to improve patient care and pave the way for new regional opportunities in pharmaceutical research and drug trials on the continent for AD.
Keywords
Africa, Alzheimer’s disease, Circulating biomarkers, Diagnosis, Low- and middle-income countries
Pubmed
Open Access
Yes
Create date
21/05/2024 14:15
Last modification date
22/05/2024 7:18
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