A robust broadband fat -suppressing phaser T2-preparation module for cardiac magnetic resonance imaging at 3T.
Details
Download: Arn_PhaserT2prep_MRM2021.pdf (1703.18 [Ko])
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Version: Final published version
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State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_F1823B94C0AF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A robust broadband fat -suppressing phaser T2-preparation module for cardiac magnetic resonance imaging at 3T.
Journal
Magnetic resonance in medicine
ISSN
1522-2594 (Electronic)
ISSN-L
0740-3194
Publication state
Published
Issued date
09/2021
Peer-reviewed
Oui
Volume
86
Number
3
Pages
1434-1444
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Designing a new T <sub>2</sub> -preparation (T <sub>2</sub> -Prep) module to simultaneously provide robust fat suppression and efficient T <sub>2</sub> preparation without requiring an additional fat-suppression module for T <sub>2</sub> -weighted imaging at 3T.
The tip-down radiofrequency (RF) pulse of an adiabatic T <sub>2</sub> -Prep module was replaced by a custom-designed RF-excitation pulse that induces a phase difference between water and fat, resulting in a simultaneous T <sub>2</sub> preparation of water signals and the suppression of fat signals at the end of the module (a phaser adiabatic T <sub>2</sub> -Prep). Numerical simulations and in vitro and in vivo electrocardiogram (ECG)-triggered navigator-gated acquisitions of the human heart were performed. Blood, myocardium, and fat signal-to-noise ratios and right coronary artery vessel sharpness were compared against previously published adiabatic T <sub>2</sub> -Prep approaches.
Numerical simulations predicted an increased fat-suppression bandwidth and decreased sensitivity to transmit magnetic field inhomogeneities using the proposed approach while preserving the water T <sub>2</sub> -Prep capabilities. This was confirmed by the tissue signals acquired in the phantom and the in vivo images, which show similar blood and myocardium signal-to-noise ratio, contrast-to-noise ratio, and significantly reduced fat signal-to-noise ratio compared with the other methods. As a result, the right coronary artery conspicuity was significantly increased.
A novel fat-suppressing T <sub>2</sub> -Prep method was developed and implemented that showed robust fat suppression and increased vessel sharpness compared with conventional techniques while preserving its T <sub>2</sub> -Prep capabilities.
The tip-down radiofrequency (RF) pulse of an adiabatic T <sub>2</sub> -Prep module was replaced by a custom-designed RF-excitation pulse that induces a phase difference between water and fat, resulting in a simultaneous T <sub>2</sub> preparation of water signals and the suppression of fat signals at the end of the module (a phaser adiabatic T <sub>2</sub> -Prep). Numerical simulations and in vitro and in vivo electrocardiogram (ECG)-triggered navigator-gated acquisitions of the human heart were performed. Blood, myocardium, and fat signal-to-noise ratios and right coronary artery vessel sharpness were compared against previously published adiabatic T <sub>2</sub> -Prep approaches.
Numerical simulations predicted an increased fat-suppression bandwidth and decreased sensitivity to transmit magnetic field inhomogeneities using the proposed approach while preserving the water T <sub>2</sub> -Prep capabilities. This was confirmed by the tissue signals acquired in the phantom and the in vivo images, which show similar blood and myocardium signal-to-noise ratio, contrast-to-noise ratio, and significantly reduced fat signal-to-noise ratio compared with the other methods. As a result, the right coronary artery conspicuity was significantly increased.
A novel fat-suppressing T <sub>2</sub> -Prep method was developed and implemented that showed robust fat suppression and increased vessel sharpness compared with conventional techniques while preserving its T <sub>2</sub> -Prep capabilities.
Keywords
Coronary Vessels, Heart/diagnostic imaging, Humans, Magnetic Resonance Angiography, Magnetic Resonance Imaging, Phantoms, Imaging, 3T magnetic resonance imaging (MRI), T2 preparation, adiabatic, angiography, coronary, fat suppression, noncontrast
Pubmed
Web of science
Create date
30/03/2021 9:02
Last modification date
06/08/2024 7:19