Approach to oligometastatic disease in head and neck cancer, on behalf of the GORTEC.

Details

Serval ID
serval:BIB_F163EA163C89
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Approach to oligometastatic disease in head and neck cancer, on behalf of the GORTEC.
Journal
Future oncology
Author(s)
Sun X.S., Michel C., Babin E., De Raucourt D., Péchery A., Gherga E., Géry B., Florescu C., Bourhis J., Thariat J.
ISSN
1744-8301 (Electronic)
ISSN-L
1479-6694
Publication state
Published
Issued date
04/2018
Peer-reviewed
Oui
Volume
14
Number
9
Pages
877-889
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Median survival for recurrent/metastatic head and neck squamous cell cancer (HNSCC) patients is about 10 months after first-line best systemic treatment. We aimed to assess current approaches of oligometastatic HNSCC patients by the analysis of current concept and published data (1995-2017) in this population. Five-year survival rates are over 20% in selected patients who undergo metastasis-directed therapy by either surgery or stereotactic irradiation. Human papillomavirus(+) HNSCC patients have more disseminated metastases but respond more favorably and also benefit from ablative treatments. Treatments of oligometastases are expanding rapidly. Unmet needs include revised imaging follow-up strategies to detect metastases earlier, identification of predictive noninvasive biomarkers for treatment guidance, assessment and corrections of biases in current studies and randomized clinical trials.
Keywords
Biomarkers, Tumor/genetics, Carcinoma, Squamous Cell/drug therapy, Carcinoma, Squamous Cell/genetics, Carcinoma, Squamous Cell/radiotherapy, Carcinoma, Squamous Cell/surgery, Head and Neck Neoplasms/drug therapy, Head and Neck Neoplasms/genetics, Head and Neck Neoplasms/radiotherapy, Head and Neck Neoplasms/surgery, Humans, Neoplasm Metastasis, Neoplasm Recurrence, Local/drug therapy, Neoplasm Recurrence, Local/genetics, Neoplasm Recurrence, Local/radiotherapy, Neoplasm Recurrence, Local/surgery, Radiosurgery, Randomized Controlled Trials as Topic, ablative treatment, head and neck cancer, immunotherapy, metastasectomy, metastases, metastasis-directed treatment, oligometastases, stereotactic irradiation
Pubmed
Web of science
Create date
29/03/2018 18:50
Last modification date
05/11/2018 7:26
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