No major impact of skin aging on the response of skin blood flow to a submaximal local thermal stimulus.

Details

Serval ID
serval:BIB_F137017D5A34
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
No major impact of skin aging on the response of skin blood flow to a submaximal local thermal stimulus.
Journal
Microcirculation
Author(s)
Vionnet J., Calero-Romero I., Heim A., Rotaru C., Engelberger R.P., Dischl B., Noël B., Liaudet L., Waeber B., Feihl F.
ISSN
1549-8719 (Electronic)
ISSN-L
1073-9688
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
21
Number
8
Pages
730-737
Language
english
Notes
Publication types: Journal Article
Abstract
OBJECTIVE: This study was undertaken to investigate how aging affects dermal microvascular reactivity in skin areas differentially exposed to sunlight, and therefore to different degrees of photoaging.
METHODS: We assessed, in young (18-30 years, n = 13) and aged males (≥60 years, n = 13), the thigh, forearm, and forehead's skin vasodilatory response to local heating (LTH) with a LDI. In each subject and at each location, local Tskin was brought from 34°C (baseline) to 39 or 41°C for 30 minutes, to effect submaximal vasodilation, with maximal vasodilation then elicited by further heating to 44°C.
RESULTS: The CVCs evaluated at baseline and after maximal vasodilation (CVCmax ) were higher in the forehead than in the two other anatomical locations. On all locations, CVCmax decreased with age but less markedly in the forehead compared to the two other locations. When expressed in % of CVCmax , the plateau increase of CVCs in response to submaximal temperatures (39 and 41°C) did not vary with age, and minimally so with location.
CONCLUSION: Skin aging, whether intrinsic or combined with photoaging, reduces the maximal vasodilatory capacity of the dermal microcirculation, but not its reactivity to local heating.
Pubmed
Web of science
Create date
10/12/2014 15:35
Last modification date
20/08/2019 17:18
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