Predictors for hospitalization and outpatient visits in patients with inflammatory bowel disease: results from the Swiss Inflammatory Bowel Disease Cohort Study.
Details
Serval ID
serval:BIB_F11DFFB6BADE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Predictors for hospitalization and outpatient visits in patients with inflammatory bowel disease: results from the Swiss Inflammatory Bowel Disease Cohort Study.
Journal
European Journal of Gastroenterology and Hepatology
Working group(s)
Swiss IBD Cohort Study Group
Contributor(s)
Aepli P., Ballabeni P., Bareiss D., Bauerfeind P., Beglinger C., Begré S., Bengoa J., Binek J., Boller D., Borovicka J., Braegger C., Brun P., Bühr P., Burnand B., Camara R., Cremer M., Criblez D., de Saussure P., Degen L., Delarive J., Dörig C., Dorta G., Ehmann T., Engelmann M., El Wafa A., Felley C., Frei A., Frei P., Frei R., Fried M., Fried R., Froehlich F., Frühauf H., Gallot-Lavallée S., Gerlach T., Geyer M., Giezendanner S., Girardin M., Goetze O., Guyot J., Haack H., Halama M., Hediger S., Heer P., Helbling B., Hellstern M., Hengstler P., Heyland K., Hirschi C., Hruz P., Janiak P., Jost C., Juillerat P., Brondolo VK., Knoblauch C., Krieger C., Kubli M., Kullak-Ublick GA., Leung-Ki EL., Maerten P., Maillard M., Manz M., Marbet U., Marsteller I., Meier R., Meyenberger C., Michetti P., Mottet C., Müller C., Müller P., Müllhaupt B., Nichita C., Nicolet T., Nüesch H., Nydegger A., Ollyo JB., Oneta C., Pache I., Piccoli F., Pilz J., Pittet V., Reichlin B., Rentsch R., Rey JP., Rihs S., Rogler D., Rogler G., Rossi L., Sagmeister M., Sauter B., Sawatzki£££Mikaël£££ M. , Schaub N., Schaub N., Schibli S., Schlauri H., Schnegg JF., Schoepfer A., Seibold F., Semela D., Sidler M., Spalinger J., Stadler P., Staub P., Steuerwald M., Straumann A., Straumann-Funk B., Sulz MC., Schäppi M., Thorens£££Joël£££ J. , Tutuian R., Vader JP., Van der Weg B., Vannini S., Vavricka S., Viani F., Vögtlin J., Vouillamoz D., Von Känel R., Wachter G., Wermuth J., Wiesel P., Wildi S.
ISSN
1473-5687 (Electronic)
ISSN-L
0954-691X
Publication state
Published
Issued date
2013
Volume
25
Number
7
Pages
790-797
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
OBJECTIVES: Patients with inflammatory bowel disease (IBD) have a high resource consumption, with considerable costs for the healthcare system. In a system with sparse resources, treatment is influenced not only by clinical judgement but also by resource consumption. We aimed to determine the resource consumption of IBD patients and to identify its significant predictors.
MATERIALS AND METHODS: Data from the prospective Swiss Inflammatory Bowel Disease Cohort Study were analysed for the resource consumption endpoints hospitalization and outpatient consultations at enrolment [1187 patients; 41.1% ulcerative colitis (UC), 58.9% Crohn's disease (CD)] and at 1-year follow-up (794 patients). Predictors of interest were chosen through an expert panel and a review of the relevant literature. Logistic regressions were used for binary endpoints, and negative binomial regressions and zero-inflated Poisson regressions were used for count data.
RESULTS: For CD, fistula, use of biologics and disease activity were significant predictors for hospitalization days (all P-values <0.001); age, sex, steroid therapy and biologics were significant predictors for the number of outpatient visits (P=0.0368, 0.023, 0.0002, 0.0003, respectively). For UC, biologics, C-reactive protein, smoke quitters, age and sex were significantly predictive for hospitalization days (P=0.0167, 0.0003, 0.0003, 0.0076 and 0.0175 respectively); disease activity and immunosuppressive therapy predicted the number of outpatient visits (P=0.0009 and 0.0017, respectively). The results of multivariate regressions are shown in detail.
CONCLUSION: Several highly significant clinical predictors for resource consumption in IBD were identified that might be considered in medical decision-making. In terms of resource consumption and its predictors, CD and UC show a different behaviour.
MATERIALS AND METHODS: Data from the prospective Swiss Inflammatory Bowel Disease Cohort Study were analysed for the resource consumption endpoints hospitalization and outpatient consultations at enrolment [1187 patients; 41.1% ulcerative colitis (UC), 58.9% Crohn's disease (CD)] and at 1-year follow-up (794 patients). Predictors of interest were chosen through an expert panel and a review of the relevant literature. Logistic regressions were used for binary endpoints, and negative binomial regressions and zero-inflated Poisson regressions were used for count data.
RESULTS: For CD, fistula, use of biologics and disease activity were significant predictors for hospitalization days (all P-values <0.001); age, sex, steroid therapy and biologics were significant predictors for the number of outpatient visits (P=0.0368, 0.023, 0.0002, 0.0003, respectively). For UC, biologics, C-reactive protein, smoke quitters, age and sex were significantly predictive for hospitalization days (P=0.0167, 0.0003, 0.0003, 0.0076 and 0.0175 respectively); disease activity and immunosuppressive therapy predicted the number of outpatient visits (P=0.0009 and 0.0017, respectively). The results of multivariate regressions are shown in detail.
CONCLUSION: Several highly significant clinical predictors for resource consumption in IBD were identified that might be considered in medical decision-making. In terms of resource consumption and its predictors, CD and UC show a different behaviour.
Keywords
Adult, Ambulatory Care/utilization, Colitis, Ulcerative/diagnosis, Colitis, Ulcerative/epidemiology, Crohn Disease/diagnosis, Crohn Disease/epidemiology, Female, Health Resources/utilization, Hospitalization, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Prospective Studies, Referral and Consultation/utilization, Risk Factors, Switzerland/epidemiology, Time Factors
Pubmed
Web of science
Create date
07/02/2014 15:02
Last modification date
20/08/2019 16:18
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