Interventional management of gastroduodenal lesions complicating intra-arterial hepatic chemotherapy.

Details

Ressource 1Download: serval:BIB_F092E9D60282.P001 (203.55 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_F092E9D60282
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Interventional management of gastroduodenal lesions complicating intra-arterial hepatic chemotherapy.
Journal
European Radiology
Author(s)
Proietti S., De Baere T., Bessoud B., Doenz F., Qanadli S.D., Schnyder P., Denys A.
ISSN
0938-7994 (Print)
ISSN-L
0938-7994
Publication state
Published
Issued date
08/2007
Peer-reviewed
Oui
Volume
17
Number
8
Pages
2160-2165
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Herein we report the efficacy of embolization of small patent gastric or duodenal vessels for treating gastroduodenal complications after hepatic arterial infusion therapy (HAIC). Catheter ports were implanted percutaneously from a femoral approach in three cases or surgically in the gastroduodenal artery in two cases. Acute abdominal pain developed on average after four HAIC courses of 5FU-oxaliplatin, mytomycin, oxaliplatin or fotemustine. Esophagogastroduodenoscopy showed gastroduodenal lesions (gastroduodenitis with or without ulcerations) in all cases. Despite the interruption of the HAIC, symptoms persisted and led to selective hepatic arteriography showing a patent right gastric artery (n = 4) or a recanalized gastroduodenal artery (n = 1) responsible for gastroduodenal misperfusion. Successful embolizations of the arteries responsible for gastroduodenal misperfusion (right gastric artery in four cases and gastroduodenal artery in one case) using 0.018 platinium coils relieved the patients' symptoms and allowed the HAIC to continue. In gastroduodenal complications of HAIC, a selective hepatic arteriography should be performed to search any artery responsible for the misperfusion of the toxic agent in the gastroduodenal area. Embolization of these arteries allowed the HAIC to be restored.
Keywords
Adult, Aged, Antineoplastic Combined Chemotherapy Protocols/administration & dosage, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Duodenal Ulcer/chemically induced, Duodenal Ulcer/therapy, Duodenum/blood supply, Embolization, Therapeutic, Endoscopy, Gastrointestinal, Female, Femoral Artery, Humans, Infusions, Intra-Arterial, Liver Neoplasms/drug therapy, Liver Neoplasms/secondary, Male, Middle Aged, Mitomycin/administration & dosage, Mitomycin/adverse effects, Nitrosourea Compounds/administration & dosage, Nitrosourea Compounds/adverse effects, Organophosphorus Compounds/administration & dosage, Organophosphorus Compounds/adverse effects, Organoplatinum Compounds/administration & dosage, Organoplatinum Compounds/adverse effects, Stomach/blood supply, Stomach Ulcer/chemically induced, Stomach Ulcer/therapy, Treatment Outcome
Pubmed
Web of science
Open Access
Yes
Create date
11/04/2008 11:51
Last modification date
01/10/2019 6:20
Usage data