Cytology of Primary Salivary Gland-Type Tumors of the Lower Respiratory Tract: Report of 15 Cases and Review of the Literature.

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State: Public
Version: Final published version
Serval ID
serval:BIB_F01210EC2C64
Type
Article: article from journal or magazin.
Collection
Publications
Title
Cytology of Primary Salivary Gland-Type Tumors of the Lower Respiratory Tract: Report of 15 Cases and Review of the Literature.
Journal
Frontiers in medicine
Author(s)
Saglietti C., Volante M., La Rosa S., Letovanec I., Pusztaszeri M., Gatti G., Bongiovanni M.
ISSN
2296-858X
ISSN-L
2296-858X
Publication state
Published
Issued date
2017
Peer-reviewed
Oui
Volume
4
Pages
43
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Primary pulmonary salivary gland-type tumors are rare neoplasms arising from the seromucinous submucosal glands of the lower respiratory tract (LRT), the most common of which are mucoepidermoid carcinoma (MEC) and adenoid cystic carcinoma. They are morphologically indistinguishable from their salivary gland counterpart and recognizing them is a challenge, especially on cytological specimens. We analyzed 15 cases of histologically proven primary salivary gland tumors of the LRT to identify cytomorphological features and define potential diagnostic clues that might assist cytopathologists in the preoperative diagnosis of these neoplasias. Three out of the four cases of adenoid cystic carcinomas showed the characteristic tridimensional cell clusters and hyaline globules, whereas the last one did not show malignant cells; only two cases of MEC presented the three characteristic cell types (i.e., squamous, intermediate, and mucin secreting) on cytology. Since these neoplasms are rare and do not have a completely specific set of cytological features, it is important for practicing cytopathologists to be aware of the possibility of encountering them, in specimens from patients with LRT masses, in order to render the correct diagnosis.

Pubmed
Web of science
Open Access
Yes
Create date
02/05/2017 10:36
Last modification date
20/08/2019 17:17
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