Predictors of substance use reduction in an epidemiological first-episode psychosis cohort.

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State: Public
Version: author
Serval ID
serval:BIB_EF761555D90F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Predictors of substance use reduction in an epidemiological first-episode psychosis cohort.
Journal
Early Intervention In Psychiatry
Author(s)
Rebgetz S., Conus P., Hides L., Kavanagh D.J., Cotton S., Schimmelmann B.G., McGorry P.D., Lambert M.
ISSN
1751-7893 (Electronic)
ISSN-L
1751-7885
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
8
Number
4
Pages
358-365
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
AIM: To assess the predictors of a significant decrease or cessation of substance use (SU) in a treated epidemiological cohort of first-episode psychosis (FEP) patients.
METHOD: Participants were FEP patients of the Early Psychosis Prevention and Intervention Centre in Australia. Patients' medical files were reviewed using a standardized file audit. Data on 432 patients with FEP and baseline co-morbid substance use disorder (SUD) were available for analysis. Predictors of reduction/cessation of SU at follow up were examined using logistic regression analyses.
RESULTS: In univariate analyses, a reduction/cessation of SU was predicted by baseline measures reflecting higher education, employment, accommodation with others, cannabis use disorder (CUD) only (rather than poly-SUDs), better global functioning and better premorbid social and occupational functioning, later age at onset of psychosis, and a diagnosis of non-affective psychosis. In multivariate analysis, CUD alone and better premorbid social and occupational functioning remained significant predictors.
CONCLUSIONS: Addressing SUDs and social and occupational goals in people with FEP may offer opportunities to prevent SUDs becoming more severe or entrenched. Further longitudinal research on recovery from SU and FEP is needed to disentangle directions of influence and identify key targets for intervention.
Pubmed
Web of science
Create date
10/12/2013 11:44
Last modification date
20/08/2019 16:17
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