Is fluorine-18-fluorodeoxyglucose positron emission tomography useful in monitoring the response to treatment in patients with multiple myeloma?
Details
Serval ID
serval:BIB_EF690C71F2C3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Is fluorine-18-fluorodeoxyglucose positron emission tomography useful in monitoring the response to treatment in patients with multiple myeloma?
Journal
International journal of hematology
ISSN
1865-3774 (Electronic)
ISSN-L
0925-5710
Publication state
Published
Issued date
12/2012
Peer-reviewed
Oui
Volume
96
Number
6
Pages
685-691
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
Fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) is a useful diagnostic tool for the staging of patients with multiple myeloma (MM). The aim of this study is to perform a systematic review of the usefulness of FDG-PET or PET/CT in monitoring response to treatment in patients with MM. A comprehensive computer literature search of the PubMed/MEDLINE, Scopus and Embase databases was carried out to identify relevant peer-reviewed articles on the use of FDG-PET or PET/CT in monitoring the response to treatment in patients with MM. Ten studies described investigations of the role of FDG-PET or PET/CT in monitoring the response to treatment in 690 patients with MM or solitary plasmacytoma: six of these were conducted prospectively, while four studies were retrospective. These articles were retrieved in full-text version and analyzed. Based on these findings from the literature, FDG-PET or PET/CT appear to be useful in the assessment of treatment response in patients with MM.
Keywords
Aged, Bone Marrow/diagnostic imaging, Bone Marrow/metabolism, Bone Neoplasms/diagnostic imaging, Bone Neoplasms/metabolism, Bone Neoplasms/secondary, Clinical Trials as Topic, Combined Modality Therapy, Disease-Free Survival, Female, Fluorine Radioisotopes, Fluorodeoxyglucose F18, Glycolysis, Humans, Male, Meta-Analysis as Topic, Middle Aged, Multimodal Imaging, Multiple Myeloma/diagnostic imaging, Multiple Myeloma/metabolism, Multiple Myeloma/pathology, Multiple Myeloma/therapy, Neoplasm Staging/methods, Plasmacytoma/diagnostic imaging, Plasmacytoma/metabolism, Plasmacytoma/pathology, Plasmacytoma/therapy, Positron-Emission Tomography, Prognosis, Prospective Studies, Radiopharmaceuticals, Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome
Pubmed
Web of science
Create date
20/08/2017 21:16
Last modification date
20/08/2019 17:17
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