Is fluorine-18-fluorodeoxyglucose positron emission tomography useful in monitoring the response to treatment in patients with multiple myeloma?

Details

Serval ID
serval:BIB_EF690C71F2C3
Type
Article: article from journal or magazin.
Collection
Publications
Title
Is fluorine-18-fluorodeoxyglucose positron emission tomography useful in monitoring the response to treatment in patients with multiple myeloma?
Journal
International journal of hematology
Author(s)
Caldarella C., Isgrò M.A., Treglia I., Treglia G.
ISSN
1865-3774 (Electronic)
ISSN-L
0925-5710
Publication state
Published
Issued date
12/2012
Peer-reviewed
Oui
Volume
96
Number
6
Pages
685-691
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) is a useful diagnostic tool for the staging of patients with multiple myeloma (MM). The aim of this study is to perform a systematic review of the usefulness of FDG-PET or PET/CT in monitoring response to treatment in patients with MM. A comprehensive computer literature search of the PubMed/MEDLINE, Scopus and Embase databases was carried out to identify relevant peer-reviewed articles on the use of FDG-PET or PET/CT in monitoring the response to treatment in patients with MM. Ten studies described investigations of the role of FDG-PET or PET/CT in monitoring the response to treatment in 690 patients with MM or solitary plasmacytoma: six of these were conducted prospectively, while four studies were retrospective. These articles were retrieved in full-text version and analyzed. Based on these findings from the literature, FDG-PET or PET/CT appear to be useful in the assessment of treatment response in patients with MM.

Keywords
Aged, Bone Marrow/diagnostic imaging, Bone Marrow/metabolism, Bone Neoplasms/diagnostic imaging, Bone Neoplasms/metabolism, Bone Neoplasms/secondary, Clinical Trials as Topic, Combined Modality Therapy, Disease-Free Survival, Female, Fluorine Radioisotopes, Fluorodeoxyglucose F18, Glycolysis, Humans, Male, Meta-Analysis as Topic, Middle Aged, Multimodal Imaging, Multiple Myeloma/diagnostic imaging, Multiple Myeloma/metabolism, Multiple Myeloma/pathology, Multiple Myeloma/therapy, Neoplasm Staging/methods, Plasmacytoma/diagnostic imaging, Plasmacytoma/metabolism, Plasmacytoma/pathology, Plasmacytoma/therapy, Positron-Emission Tomography, Prognosis, Prospective Studies, Radiopharmaceuticals, Retrospective Studies, Tomography, X-Ray Computed, Treatment Outcome
Pubmed
Web of science
Create date
20/08/2017 21:16
Last modification date
03/03/2018 22:34
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