Sedimentation of macroscopic rigid knots and its relation to gel electrophoretic mobility of DNA knots.

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Serval ID
serval:BIB_EF01E9CB67B3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Sedimentation of macroscopic rigid knots and its relation to gel electrophoretic mobility of DNA knots.
Journal
Scientific Reports
Author(s)
Weber C., Carlen M., Dietler G., Rawdon E.J., Stasiak A.
ISSN
2045-2322 (Electronic)
ISSN-L
2045-2322
Publication state
Published
Issued date
2013
Volume
3
Pages
1091
Language
english
Abstract
We address the general question of the extent to which the hydrodynamic behaviour of microscopic freely fluctuating objects can be reproduced by macrosopic rigid objects. In particular, we compare the sedimentation speeds of knotted DNA molecules undergoing gel electrophoresis to the sedimentation speeds of rigid stereolithographic models of ideal knots in both water and silicon oil. We find that the sedimentation speeds grow roughly linearly with the average crossing number of the ideal knot configurations, and that the correlation is stronger within classes of knots. This is consistent with previous observations with DNA knots in gel electrophoresis.
Pubmed
Web of science
Open Access
Yes
Create date
28/02/2013 10:59
Last modification date
20/08/2019 16:16
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