Depression, migraine with aura and migraine without aura: their familiality and interrelatedness.
Details
Serval ID
serval:BIB_EE91195698BC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Depression, migraine with aura and migraine without aura: their familiality and interrelatedness.
Journal
Cephalalgia : an international journal of headache
ISSN
1468-2982[electronic]
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
29
Number
8
Pages
848-54
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
Migraine is frequently comorbid with depression. There appear to be common aetiological factors for both disorders, but the aetiology of migraine within depressed patients, in particular the significance of aura, has been little studied. A large sample of concordantly depressed sibling pairs [the Depression-Network (DeNT) sample] was assessed as having migraine with aura (MA), migraine without aura (MoA), probable migraine or no migraine according to International Headache Society guidelines. Correlations between siblings' migraine status were used to assess the nature of familial liability to migraine. A multiple threshold isocorrelational model fit best, in which different syndromes are conceptualized as different severities of one underlying dimension rather than as having separate aetiologies. Thus, MA and MoA were found to be different forms of the same disorder, with MA occupying the more extreme end of the spectrum of liability. Implications for our understanding of the relationship between migraine and depression are discussed.
Pubmed
Web of science
Create date
20/07/2009 9:04
Last modification date
20/08/2019 17:16