Outcomes in neurosurgical patients who develop venous thromboembolism: a review of the RIETE registry.
Details
Serval ID
serval:BIB_ECE77A86D018
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Outcomes in neurosurgical patients who develop venous thromboembolism: a review of the RIETE registry.
Journal
Clinical and Applied Thrombosis/hemostasis
Working group(s)
RIETE Investigators
Contributor(s)
Arcelus JI., Ballaz A., Barba R., Barrón M., Barrón-Andrés B., Bascuñana J., Bedate P., Blanco-Molina A., Bueso T., Casado I., Conget F., del Molino F., del Toro J., Falgá C., Fernández-Capitán C., Font C., Fuentes MI., Gallego P., García-Bragado F., Gavín O., Gómez V., González J., González-Bachs E., Grau E., Guil M., Guijarro R., Gutiérrez J., Hernández L., Hernández-Huerta S., Jara-Palomares L., Jaras MJ., Jiménez D., Lobo JL., López-Jiménez L., López-Sáez JB., Lorente MA., Lorenzo A., Luque JM., Madridano O., Macià M., Maestre A., Marchena PJ., Martín M., Monreal M., Mora JM., Mosquera D., Muñoz FJ., Nauffal MD., Nieto JA., Núñez MJ., Ogea JL., Otero R., Pedrajas JM., Peris ML., Raissouni N., Riera-Mestre A., Rivas A., Rodríguez-Dávila MA., Román P., Rosa V., Ruiz J., Ruiz-Ribó MD., Ruiz-Gamietea A., Ruiz-Giménez N., Sahuquillo JC., Samperiz A., Sánchez Muñoz-Torrero JF. , Soler S., Tiberio G., Tilvan RM., Tolosa C., Trujillo J., Uresandi F., Valdés M., Valero B., Valle R., Vela J., Villalobos A., Villalta J., Malý R., Hirmerova J., Bertoletti L., Bura-Riviere A., Farge-Bancel D., Grange C., Hij A., Mahe I., Merah A., Quere I., Schellong S., Babalis D., Papadakis M., Tzinieris I., Braester A., Brenner B., Tzoran I., Zeltser D., Barillari G., Ciammaichella M., Di Micco P., Duce R., Pasca S., Pesavento R., Piovella C., Poggio R., Prandoni P., Quintavalla R., Rocci A., Rota L., Schenone A., Tiraferri E., Tonello D., Tufano A., Visonà A., Zalunardo B., Barbosa AL., Gonçalves F., Rodrigues AM., Santos M., Saraiva M., Bosevski M., Kovacevic D., Alatri A., Aujeski D., Bounameaux H., Calanca L., Mazzolai L., Caprini J.
ISSN
1938-2723 (Electronic)
ISSN-L
1076-0296
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
20
Number
8
Pages
772-778
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
Abstract
OBJECTIVES: Registro Informatizado de Enfermedad TromboEmbólica (RIETE) database was used to investigate whether neurosurgical patients with venous thromboembolism (VTE) were more likely to die of bleeding or VTE and the influence of anticoagulation on these outcomes.
METHODS: Clinical characteristics, treatment details, and 3-month outcomes were assessed in those who developed VTE after neurosurgery.
RESULTS: Of 40 663 patients enrolled, 392 (0.96%) had VTE in less than 60 days after neurosurgery. Most patients in the cohort (89%) received initial therapy with low-molecular-weight heparin, (33% received subtherapeutic doses). In the first week, 10 (2.6%) patients died (8 with pulmonary embolism [PE], no bleeding deaths; P = .005). After the first week, 20 (5.1%) patients died (2 with fatal bleeding, none from PE). Overall, this cohort was more likely to develop a fatal PE than a fatal bleed (8 vs 2 deaths, P = .058).
CONCLUSIONS: Neurosurgical patients developing VTE were more likely to die from PE than from bleeding in the first week, despite anticoagulation.
METHODS: Clinical characteristics, treatment details, and 3-month outcomes were assessed in those who developed VTE after neurosurgery.
RESULTS: Of 40 663 patients enrolled, 392 (0.96%) had VTE in less than 60 days after neurosurgery. Most patients in the cohort (89%) received initial therapy with low-molecular-weight heparin, (33% received subtherapeutic doses). In the first week, 10 (2.6%) patients died (8 with pulmonary embolism [PE], no bleeding deaths; P = .005). After the first week, 20 (5.1%) patients died (2 with fatal bleeding, none from PE). Overall, this cohort was more likely to develop a fatal PE than a fatal bleed (8 vs 2 deaths, P = .058).
CONCLUSIONS: Neurosurgical patients developing VTE were more likely to die from PE than from bleeding in the first week, despite anticoagulation.
Pubmed
Web of science
Create date
20/02/2015 10:41
Last modification date
20/08/2019 16:14
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