Recurrence due to neoplastic seeding in head and neck cancer: report of two cases and review of the literature.

Details

Serval ID
serval:BIB_EC72F2CAC8EA
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Recurrence due to neoplastic seeding in head and neck cancer: report of two cases and review of the literature.
Journal
Tumori
Author(s)
Nisa L., Khanfir K., Giger R.
ISSN
2038-2529 (Electronic)
ISSN-L
0300-8916
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
99
Number
4
Pages
e144-7
Language
english
Notes
Publication types: Case Reports ; Journal Article ; Review
Publication Status: ppublish
Abstract
Tumor progression due to seeding of tumor cells after definitive treatment for squamous cell carcinomas of the head and neck is an uncommon condition that can considerably worsen the outcome of patients with head and neck cancer.
We report two cases of recurrence due to neoplastic seeding from oropharyngeal and oral cancer, respectively. We performed a literature review with MEDLINE as the main search engine.
Seeding was found to occur most often in tracheotomy scars and gastrostomy sites. The oral cavity, hypopharynx and oropharynx were the primary sites in most cases, and advanced tumor stage seemed to be a risk factor for seeding. Treatment options include salvage surgery, which requires thorough resections, radiotherapy when possible, and palliative management. The prognosis of such events is poor.
Although neoplastic seeding is a well-known phenomenon in cancer surgery, many questions remain unanswered, especially regarding preventive measures and management strategies.
Keywords
Carcinoma, Squamous Cell/diagnosis, Carcinoma, Squamous Cell/radiotherapy, Carcinoma, Squamous Cell/surgery, Carcinoma, Squamous Cell/therapy, Fatal Outcome, Head and Neck Neoplasms/diagnosis, Head and Neck Neoplasms/radiotherapy, Head and Neck Neoplasms/surgery, Head and Neck Neoplasms/therapy, Humans, Lymphatic Metastasis, Male, Middle Aged, Mouth Neoplasms/therapy, Neck Dissection, Neoplasm Recurrence, Local/diagnosis, Neoplasm Seeding, Neoplasm Staging, Palliative Care, Reoperation, Retreatment, Salvage Therapy/methods, Tonsillar Neoplasms/therapy, Tracheotomy, Treatment Outcome
Pubmed
Create date
18/10/2019 16:28
Last modification date
19/10/2019 6:26
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