Inappropriate antidiuretic hormone secretion: long-term successful urea treatment.

Details

Serval ID
serval:BIB_EBF520F467CB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Inappropriate antidiuretic hormone secretion: long-term successful urea treatment.
Journal
Acta Paediatrica
Author(s)
Chehade H., Rosato L., Girardin E., Cachat F.
ISSN
1651-2227 (Electronic)
ISSN-L
0803-5253
Publication state
Published
Issued date
2012
Volume
101
Number
1
Pages
e39-e42
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication type: Journal Article validé par V. Mooser le 29.01.2014.
Abstract
Hyponatremia is the main complication of inappropriate antidiuretic hormone secretion (SIADH), sometimes fatal. Treatment strategy depends on the cause and the severity of the hyponatremia. Recent studies have shown the efficacy of urea in treating acute hyponatremia secondary to SIADH, by inducing an osmotic water drive. We describe an infant with chronic hyponatremia secondary to SIADH in which the long-term oral treatment with urea was successful and well tolerated. The aim of this paper is to highlight the potential benefits of urea treatment in case of chronic hyponatremia secondary to SIADH. CONCLUSION: Chronic oral urea treatment in children with SIADH allows an easy and safe water and sodium control and may permit a decrease in fluid restriction in this situation.
Keywords
Child, Preschool, Chronic Disease, Diuretics, Osmotic/therapeutic use, Female, Humans, Hyponatremia/drug therapy, Hyponatremia/etiology, Inappropriate ADH Syndrome/complications, Infant, Infant, Newborn, Long-Term Care, Treatment Outcome, Urea/therapeutic use
Pubmed
Web of science
Create date
04/09/2011 16:04
Last modification date
20/08/2019 17:14
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