Metabolic communication in the tumour-immune microenvironment.

Details

Serval ID
serval:BIB_EA98D2D63E56
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Metabolic communication in the tumour-immune microenvironment.
Journal
Nature cell biology
Author(s)
Kao K.C., Vilbois S., Tsai C.H., Ho P.C.
ISSN
1476-4679 (Electronic)
ISSN-L
1465-7392
Publication state
In Press
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: aheadofprint
Abstract
The metabolically hostile tumour microenvironment imposes barriers to tumour-infiltrating immune cells and impedes durable clinical remission following immunotherapy. Metabolic communication between cancer cells and their neighbouring immune cells could determine the amplitude and type of immune responses, highlighting a potential involvement of metabolic crosstalk in immune surveillance and escape. In this Review, we explore tumour-immune metabolic crosstalk and discuss potential nutrient-limiting strategies that favour anti-tumour immune responses.
Pubmed
Web of science
Create date
25/10/2022 13:36
Last modification date
02/11/2022 6:41
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