Intrainsular functional connectivity in human

Details

Serval ID
serval:BIB_EA97A40BBCE1
Type
Article: article from journal or magazin.
Collection
Publications
Title
Intrainsular functional connectivity in human
Journal
Hum Brain Mapp
Author(s)
Almashaikhi T., Rheims S., Ostrowsky-Coste K., Montavont A., Jung J., De Bellescize J., Arzimanoglou A., Keo Kosal P., Guenot M., Bertrand O., Ryvlin P.
ISSN
1097-0193 (Electronic)
ISSN-L
1065-9471
Publication state
Published
Issued date
06/2014
Volume
35
Number
6
Pages
2779-88
Language
english
Notes
Almashaikhi, Talal
Rheims, Sylvain
Ostrowsky-Coste, Karine
Montavont, Alexandra
Jung, Julien
De Bellescize, Julitta
Arzimanoglou, Alexis
Keo Kosal, Pascal
Guenot, Marc
Bertrand, Olivier
Ryvlin, Philippe
eng
Hum Brain Mapp. 2014 Jun;35(6):2779-88. doi: 10.1002/hbm.22366. Epub 2013 Sep 12.
Abstract
OBJECTIVES: The anatomical organization of the insular cortex is characterized by its rich and heterogeneous cytoarchitecture and its wide network of connections. However, only limited knowledge is available regarding the intrainsular connections subserving the complex integrative role of the insular cortex. The aim of this study was to analyze the functional connectivity within- and across-insular subregions, at both gyral and functional levels. EXPERIMENTAL DESIGN: We performed intracerebral electrical stimulation in 10 patients with refractory epilepsy investigated with depth electrodes, 38 of which were inserted in the insula. Bipolar electrical stimulation, consisting of two series of 20 pulses of 1-ms duration, 0.2-Hz frequency, and 1-mA intensity, was delivered at each insular contact. For each stimulated insular anatomical region, we calculated a rate of connectivity, reflecting the proportion of other insular contacts, showing significant evoked potentials. RESULTS: Statistically significant evoked potentials were recorded in 74% of tested connections, with an average latency of 26 +/- 3 ms. All insular gyri were interconnected, except the anterior and posterior short gyri. Most connections were reciprocal, showing no clear anterior to posterior directionality. No connection was observed between the right and the left insula. CONCLUSIONS: These findings point to specific features of human insula connectivity as compared to non-Human primates, and remain consistent with the complex integration role devoted to the human insula in many cognitive domains. Periodicals, Inc.
Keywords
Cerebral Cortex/*physiology, Electric Stimulation, Electrodes, Implanted, Electroencephalography, Epilepsies, Partial/physiopathology, Evoked Potentials, Functional Laterality, Humans, Neural Pathways/physiology, Signal Processing, Computer-Assisted, evoked potential, functional connectivity, human, insular, intra-cranial electrical stimulation
Pubmed
Create date
29/11/2018 12:36
Last modification date
20/08/2019 16:13
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