Gait Performance and Use of Mental Imagery as a Measure of Disease Progression in Amyotrophic Lateral Sclerosis.

Details

Serval ID
serval:BIB_E9CA6F73A5E7
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Gait Performance and Use of Mental Imagery as a Measure of Disease Progression in Amyotrophic Lateral Sclerosis.
Journal
European neurology
Author(s)
Iancu Ferfoglia R., Heritier Barras A.C., Pollak P., Janssens J.P., Pradat P.F., Allali G.
ISSN
1421-9913 (Electronic)
ISSN-L
0014-3022
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
75
Number
3-4
Pages
109-112
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Gait and balance are key determinants of disease status in amyotrophic lateral sclerosis (ALS). This study aims at testing the relationship between the imagery of gait and disability in patients with ALS.
Twenty-five consecutive patients (63.8 ± 2.4 years; 52% female) performed the timed up and go (TUG) test and a validated imagined version of the TUG between March 2011 and May 2012. The revised ALS functional rating score (ALSFRS-R) was assessed simultaneously.
The mean duration of TUG (16.7 ± 2.2 s) was significantly longer than imagined TUG (iTUG; 10.5 ± 1.4 s, p < 0.001). The TUG (R2 = 0.40, p = 0.001) and the iTUG (R2 = 0.30, p = 0.007) were significantly associated with results of the ALSFRS-R score (37.0 ± 7.3) as well as with muscle strength in arms (TUG R2 = 0.42, p < 0.001, iTUG R2 = 0.38, p = 0.001) and legs (TUG R2 = 0.47, p < 0.001, iTUG R2 = 0.46, p < 0.001). TUG and iTUG increased with age (TUG R2 = 0.18, p = 0.04, iTUG R2 = 0.12, p = 0.05).
ALS patients performed the imagined gait faster than the real gait. Both TUG and iTUG correlated with disability measured by the ALSFRS-R score and by muscle strength. These inexpensive and easy clinical tests represent promising tools in clinical practice to study gait in ALS.
Keywords
Adult, Amyotrophic Lateral Sclerosis/complications, Disability Evaluation, Disease Progression, Female, Gait/physiology, Humans, Imagination, Male, Middle Aged
Pubmed
Web of science
Create date
06/10/2023 9:04
Last modification date
07/10/2023 6:58
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