[Functional imaging in idiopathic generalized epilepsy]

Details

Serval ID
serval:BIB_E6A640B0DD26
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
[Functional imaging in idiopathic generalized epilepsy]
Journal
Rev Neurol (Paris)
Author(s)
Ryvlin P., Mauguiere F.
ISSN
0035-3787 (Print)
ISSN-L
0035-3787
Publication state
Published
Issued date
10/1998
Volume
154
Number
10
Pages
691-3
Language
english
Notes
Ryvlin, P
Mauguiere, F
fre
Review
France
Rev Neurol (Paris). 1998 Oct;154(10):691-3.
Abstract
Positron emission tomography has offered the possibility to investigate the pathophysiology of idiopathic generalized epilepsies. Absence epilepsies demonstrate normal cerebral glucose metabolism and benzodiazepine receptor density. Conversely, juvenile myoclonic epilepsies are associated with frontal hypometabolism, which aggravates during a working memory task. Typical 3 Hz spike and wave discharges lead to a diffuse hypermetabolism. The latter resembles that observed during GAERS rats absences, and clearly differs from the hypometabolism encountered in partial epilepsies associated with generalized spike and wave discharges. Overall, functional imaging data provide further evidence of syndromic specificities in idiopathic generalized epilepsies.
Keywords
Animals, Brain/*metabolism, Epilepsy, Generalized/*diagnostic imaging/etiology/metabolism, Glucose/*metabolism, Humans, Rats, Receptors, GABA-A/*metabolism, *Tomography, Emission-Computed
Pubmed
Create date
29/11/2018 12:37
Last modification date
20/08/2019 16:09
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