Cardiologie. Tests de réactivité plaquettaire: mise à jour pour le praticien [Cardiology. Platelet function testing for clinicians].

Details

Serval ID
serval:BIB_E5B0BC3C5BE3
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Cardiologie. Tests de réactivité plaquettaire: mise à jour pour le praticien [Cardiology. Platelet function testing for clinicians].
Journal
Revue Médicale Suisse
Author(s)
Pellaton C., Eeckhout E., Silvain J., Montalescot G., Collet J.P.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2014
Volume
10
Number
412-413
Pages
24-31
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review Publication Status: ppublishPublication Type English Abstract. Journal Article. Review.
Abstract
Platelet P2YI2 receptor inhibition with clopidogrel, prasugrel or ticagrelor plays a key role to prevent recurrent ischaemic events after percutaneous coronary intervention in acute coronary syndromes or elective settings. The degree of platelet inhibition depends on the antiplatelet medication used and is influenced by clinical and genetic factors. A concept of therapeutic window exists. On one side, efficient anti-aggregation is required in order to reduce cardio-vascular events. On the other side, an excessive platelet inhibition represents a risk of bleeding complications. This article describes the current knowledge about some platelet function tests and genetic tests and summarises their role in the clinical practice.
Keywords
Cardiology/methods, Cardiology/trends, Genetic Testing, Humans, Percutaneous Coronary Intervention/methods, Percutaneous Coronary Intervention/rehabilitation, Platelet Activation/drug effects, Platelet Activation/genetics, Platelet Aggregation Inhibitors/therapeutic use, Platelet Function Tests/utilization, Professional Practice/trends, Ticlopidine/analogs & derivatives, Ticlopidine/therapeutic use, Treatment Outcome
Pubmed
Create date
25/05/2014 15:08
Last modification date
20/08/2019 16:09
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