Gadolinium-enhanced pulmonary magnetic resonance angiography in the diagnosis of acute pulmonary embolism: a prospective study on 48 patients.

Details

Serval ID
serval:BIB_E59D850D73E1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Gadolinium-enhanced pulmonary magnetic resonance angiography in the diagnosis of acute pulmonary embolism: a prospective study on 48 patients.
Journal
Clinical imaging
Author(s)
Pleszewski B., Chartrand-Lefebvre C., Qanadli S.D., Déry R., Perreault P., Oliva V.L., Prenovault J., Belblidia A., Soulez G.
ISSN
0899-7071
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
30
Number
3
Pages
166-72
Language
english
Notes
Publication types: Clinical Trial ; Comparative Study ; Journal Article - Publication Status: ppublish
Abstract
OBJECTIVE: Gadolinium-enhanced pulmonary magnetic resonance angiography (MRA) can be an option in patients with a history of previous adverse reaction to iodinated contrast material and renal insufficiency. Radiation is also avoided. The aim of this study is to prospectively compare the diagnostic value of MRA with that of a diagnostic strategy, taking into account catheter angiography, computed tomography angiography (CTA), and lung scintigraphy [ventilation-perfusion (VQ)]. MATERIAL AND METHODS: Magnetic resonance angiography was done in 48 patients with clinically suspected pulmonary embolism (PE) using fast gradient echo coronal acquisition with gadolinium. Interpretation was done with native coronal images and multiplanar maximum intensity projection reconstructions. Results were compared to catheter angiography (n=15), CTA (n=34), VQ (n=45), as well as 6-12 months clinical follow-ups, according to a sequenced reference tree. RESULTS: The final diagnosis of PE was retained in 11 patients (23%). There were two false negatives and no false positive results with MRA. Computed tomography angiography resulted in no false negatives or false positives. Magnetic resonance angiography had a sensitivity of 82% and a specificity of 100%. CONCLUSION: In our study, pulmonary MRA had a sensitivity of 82% and a specificity of 100% for the diagnosis of PE, with slightly less sensitivity than CTA. In the diagnostic algorithm of PE, pulmonary MRA should be considered as an alternative to CTA when iodine contrast injection or radiation is a significant matter.
Keywords
Acute Disease, Adult, Aged, Aged, 80 and over, Contrast Media, Female, Follow-Up Studies, Gadolinium DTPA, Humans, Image Interpretation, Computer-Assisted, Magnetic Resonance Angiography, Male, Middle Aged, Observer Variation, Prospective Studies, Pulmonary Artery, Pulmonary Embolism, Reproducibility of Results, Sensitivity and Specificity, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
11/04/2008 12:23
Last modification date
20/08/2019 16:08
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