Hypertension in Chronic Kidney Disease - Role of Arterial Calcification and Impact on Treatment.

Details

Serval ID
serval:BIB_E57B54E0E887
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hypertension in Chronic Kidney Disease - Role of Arterial Calcification and Impact on Treatment.
Journal
European cardiology
Author(s)
Phan O., Burnier M., Wuerzner G.
ISSN
1758-3764 (Electronic)
ISSN-L
1758-3756
Publication state
Published
Issued date
12/2014
Peer-reviewed
Oui
Volume
9
Number
2
Pages
115-119
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Hypertension contributes to the progression of kidney diseases as well as to the occurrence of cardiovascular events such as myocardial infarction, heart failure and stroke. The prevalence of hypertension is elevated in patients with kidney disease, and increases progressively as glomerular filtration rate falls. A better understanding of the mechanisms leading to hypertension in renal diseases has been gained in recent years; in this article we will review the pathogenesis of hypertension in chronic kidney disease (CKD) with a special focus on vascular calcification because calcification is associated with an increased incidence of cardiovascular morbidity in CKD patients. Although calcification of large arteries and blood pressure increase with age, few studies have specifically investigated a possible connection between these two factors as determinants of the severity of hypertension in CKD. Finally, we will review the trends in hypertension treatment in CKD patients. Expanded understanding of the role of CKD as both a cause and a target of hypertension highlights key points of pathophysiology of hypertension and may contribute to the identification of new strategies for its prevention and treatment.
Keywords
Hypertension, chronic kidney disease, proteinuria, treatment, vascular calcification
Pubmed
Create date
17/10/2018 9:35
Last modification date
20/08/2019 16:08
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