Myocardial MIBG scintigraphy: a useful clinical tool? : A retrospective study in 50 parkinsonian patients.

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Serval ID
serval:BIB_E54517B63112
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Myocardial MIBG scintigraphy: a useful clinical tool? : A retrospective study in 50 parkinsonian patients.
Journal
Neurological Sciences
Author(s)
Fröhlich Ines, Pilloy Wilfried, Vaillant Michael, Diederich Nico J.
ISSN
1590-3478[electronic], 1590-1874[linking]
Publication state
Published
Issued date
2010
Volume
31
Number
3
Pages
403-406
Language
english
Notes
Correction p. 409
Abstract
Meta-iodbenzylguanidine scintigraphy (MIBG scintigraphy) shows reduced uptake in idiopathic Parkinson's disease (IPD), idiopathic REM sleep behavior disorder (IRBD) and Lewy body dementia (LBD), but not in other parkinsonian or dementia syndromes. We retrospectively reevaluated 50 patients. Concordance rate between last clinical diagnosis and scintigraphy diagnosis was only given in two-thirds of the patients. Confounding factors were: decreasing heart/mediastinum ratio (HMR) with progressive age, higher HMR in women and possibly interference with antihypertensive medication. Standardization of the methods and precise clinical guidelines are warranted for better clinical use.
Keywords
Myocardial Scintigraphy, Idiopathic Parkinson Disease, Cardiac Sympathetic Denervation, Sleep Behavior Disorder, Multiple System Atrophy, Parkinsons-Disease, I-123-MIBG Scintigraphy, Differential-Diagnosis, Consensus Statement, Lewy Bodies, Dysfunction, Dementia
Pubmed
Web of science
Open Access
Yes
Create date
31/05/2010 13:53
Last modification date
01/10/2019 6:20
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