Thermic effect of food: possible implication of parasympathetic nervous system
Details
Serval ID
serval:BIB_E49D2357C0A9
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Thermic effect of food: possible implication of parasympathetic nervous system
Journal
American Journal of Physiology
ISSN
0002-9513 (Print)
Publication state
Published
Issued date
11/1987
Volume
253
Number
5 Pt 1
Pages
E481-8
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov
Research Support, Non-U.S. Gov't --- Old month value: Nov
Abstract
To investigate the effect of the autonomic nervous system on the thermic response to food ingestion, respiratory exchange measurements were performed on seven healthy young men for 1 h and 45 min before and 6 h after ingestion of a mixed meal, approximately 560 kcal, 53% carbohydrate, 30% fat, and 17% protein (control) and under the same conditions during infusion of either propranolol (80 micrograms/kg bolus and 1 microgram.kg-1.min-1), atropine (10 micrograms/kg and 10 micrograms.kg-1.min-1), or atropine plus propranolol. The postabsorptive resting metabolic rates were the same on each occasion and were slightly altered by drug treatment. The thermic responses to the meal were the same with the control and propranolol tests (9.3 +/- 0.9 and 9.2 +/- 0.5%, respectively) and were greater (P less than 0.001) than with atropine 3.6 +/- 0.6% and atropine plus propranolol 3.3 +/- 0.8%. Blockade of the sympathetic nervous system does not decrease the thermic response to food taken orally, whereas muscarinic receptor blockade does. Although some confounding effects of atropine might explain some of this decrease, our results suggest that the parasympathetic nervous system is involved in the thermic effect of food.
Keywords
Adult
Atropine/diagnostic use
Basal Metabolism
Blood Glucose/metabolism
Blood Pressure
*Body Temperature
Energy Intake
Energy Metabolism
*Food
Heart Rate
Humans
Insulin/blood
Kinetics
Male
Oxygen Consumption
Parasympathetic Nervous System/*physiology
Propranolol/diagnostic use
Pubmed
Web of science
Create date
24/01/2008 17:53
Last modification date
20/08/2019 17:08