Examen du fond d'oeil dans le cadre d'une affection a VIH: quoi de neuf? [Examination of the posterior eye segment during HIV infection: what is new?]

Details

Serval ID
serval:BIB_E4814BA1297D
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Examen du fond d'oeil dans le cadre d'une affection a VIH: quoi de neuf? [Examination of the posterior eye segment during HIV infection: what is new?]
Journal
Klinische Monatsblatter fur Augenheilkunde
Author(s)
Guex-Crosier  Y.
ISSN
0023-2165 (Print)
Publication state
Published
Issued date
05/1999
Volume
214
Number
5
Pages
317-20
Notes
English Abstract
Journal Article
Review --- Old month value: May
Abstract
AIM: A patient was till now considered at high risk of developing a cytomegalovirus retinitis when the CD4+ cells were under 100/mm3. The risk was major when the CD4+ were under 50/mm3. With the onset of a Highly Active Antiretroviral Therapy (HAART) the follow-up of AIDS patients has changed. The introduction of a HAART is associated with an increase in CD4+ cells. The aim of the study was to highlight clinical modifications of classical AIDS associated ocular diseases. MATERIALS AND METHODS: Clinical observations will be correlated to recent data published in literature. RESULTS: An immune response can be present against opportunitic infections. Cytomegalovirus retinitis can present an atypical pattern: The host immune response can be responsible for an increase of ocular inflammation, a hypopyon can even be seen. An intense vitritis can be present and frosted angiitis syndrome can be observed. A severe macular edema can be present and has to be treated with posterior sub-Tenon's steroid injections. CONCLUSION: With the restoration of an immune response under HAART therapy, clinical manifestation of AIDS associated ocular diseases has changed and the differential diagnosis of ocular lesions must include endogenous uveitis.
Keywords
AIDS-Related Opportunistic Infections/*diagnosis/drug therapy Anti-HIV Agents/therapeutic use CD4 Lymphocyte Count Cytomegalovirus Retinitis/*diagnosis/drug therapy/immunology Diagnosis, Differential Drug Therapy, Combination Humans Risk Factors
Pubmed
Web of science
Create date
28/01/2008 12:45
Last modification date
20/08/2019 16:08
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