Accuracy of preoperative staging for a priori resectable esophageal cancer.

Details

Serval ID
serval:BIB_E41150624ED7
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Accuracy of preoperative staging for a priori resectable esophageal cancer.
Journal
Diseases of the esophagus
Author(s)
Winiker M., Mantziari S., Figueiredo S.G., Demartines N., Allemann P., Schäfer M.
ISSN
1442-2050 (Electronic)
ISSN-L
1120-8694
Publication state
Published
Issued date
01/01/2018
Peer-reviewed
Oui
Volume
31
Number
1
Pages
1-6
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
This study assessed the accuracy of preoperative staging in patients undergoing oncological esophagectomy for adenocarcinoma and squamous cell carcinoma. All patients undergoing surgery for resectable esophageal cancer in a university hospital from 2005 to 2016 were identified from our institutional database. Patients with neoadjuvant treatment were excluded to avoid bias from down-staging effects. Routinely, all patients had an upper endoscopy with biopsy, a thoracoabdominal CT scan, an 18-FEG PET-CT, and endoscopic ultrasound. Preoperative staging was compared to histopathological staging of surgical specimen that was considered as gold standard. There were 51 patients with a median age of 65 years (IQR: 59.3-73 years) having 21 squamous cell carcinoma and 30 adenocarcinoma, respectively. T- and N-stages were correctly predicted in 26 (51%) and 37 patients (72%), respectively. Overall, 18 patients (35%) were preoperatively diagnosed with a correct T- and N-stage. There was no difference between adenocarcinoma and squamous cell carcinoma. Accuracy of the T-stage was not influenced by the smoking status. The N-stage was not correct in 7/22 smoking patients (32%) and 6/29 nonsmoking patients (21%).The N-stage was underestimated in smoking patients as 6/22 patients (27%) had a histologically confirmed N+ who were preoperatively classified as N0. In conclusion, only 35% of patients had a correct assessment. Separate T- and N-stage prediction was improved with 51% and 72%, respectively. Major efforts are needed for improvement.

Keywords
esophageal cancer, esophagectomy, lymph nodes metastasis, neoadjuvant treatment, staging
Pubmed
Web of science
Create date
27/01/2018 13:19
Last modification date
14/04/2021 18:08
Usage data