SAPHO syndrome masquerading as metastatic bone disease.

Details

Serval ID
serval:BIB_E36B7D94FD35
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
SAPHO syndrome masquerading as metastatic bone disease.
Journal
Australasian Radiology
Author(s)
Theumann N.H., So A., Mouhsine E., Spoletini P., Hoesli P., Boubaker E., Duvoisin B., Schnyder P., Pugnale M.
ISSN
0004-8461
Publication state
Published
Issued date
10/2005
Peer-reviewed
Oui
Volume
49
Number
5
Pages
418-421
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
A 46-year-old woman who had had a right mastectomy for breast carcinoma a month before underwent bone scintigraphy. The examination revealed multiple pelvic, vertebral and sternal hot spots suggestive of bone metastases. Standard X-rays and CT confirmed the presence of bony lesions but they were not typical of bone metastases. As the radiographic appearance was reminiscent of SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis), bone biopsies were performed. Histology showed fibrosis and hyperostosis but no tumour cells. On further questioning, the patient revealed she had had palmar pustulosis and sacroiliitis some years earlier. The purpose of the case report is to show that accurate diagnosis of SAPHO syndrome requires careful clinical and radiological examinations.
Keywords
Acquired Hyperostosis Syndrome/diagnosis, Biopsy, Bone Neoplasms/diagnosis, Bone Neoplasms/secondary, Breast Neoplasms/pathology, Diagnosis, Differential, Female, Humans, Middle Aged
Pubmed
Create date
11/04/2008 11:40
Last modification date
20/08/2019 16:07
Usage data