The impact of spatial resolution and respiratory motion on MR imaging of atherosclerotic plaque.

Details

Serval ID
serval:BIB_E34A48705C00
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The impact of spatial resolution and respiratory motion on MR imaging of atherosclerotic plaque.
Journal
Journal of Magnetic Resonance Imaging
Author(s)
Schär M., Kim W.Y., Stuber M., Boesiger P., Manning W.J., Botnar R.M.
ISSN
1053-1807[print], 1053-1807[linking]
Publication state
Published
Issued date
2003
Volume
17
Number
5
Pages
538-544
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
PURPOSE: To examine the impact of spatial resolution and respiratory motion on the ability to accurately measure atherosclerotic plaque burden and to visually identify atherosclerotic plaque composition. MATERIALS AND METHODS: Numerical simulations of the Bloch equations and vessel wall phantom studies were performed for different spatial resolutions by incrementally increasing the field of view. In addition, respiratory motion was simulated based on a measured physiologic breathing pattern. RESULTS: While a spatial resolution of > or = 6 pixels across the wall does not result in significant errors, a resolution of < or = 4 pixels across the wall leads to an overestimation of > 20%. Using a double-inversion T2-weighted turbo spin echo sequence, a resolution of 1 pixel across equally thick tissue layers (fibrous cap, lipid, smooth muscle) and a respiratory motion correction precision (gating window) of three times the thickness of the tissue layer allow for characterization of the different coronary wall components. CONCLUSIONS: We found that measurements in low-resolution black blood images tend to overestimate vessel wall area and underestimate lumen area.
Keywords
Arteriosclerosis/diagnosis, Coronary Vessels/pathology, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging/methods, Phantoms, Imaging, Respiration
Pubmed
Web of science
Open Access
Yes
Create date
02/03/2010 16:05
Last modification date
20/08/2019 16:07
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