Horizontal vestibulo-ocular reflex dynamics in acute vestibular neuritis and viral labyrinthitis: evidence of otolith-canal interaction.

Details

Serval ID
serval:BIB_E2D0DC37FBB0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Horizontal vestibulo-ocular reflex dynamics in acute vestibular neuritis and viral labyrinthitis: evidence of otolith-canal interaction.
Journal
Acta oto-laryngologica
Author(s)
Maire R., Van Melle G.
ISSN
0001-6489
Publication state
Published
Issued date
2004
Peer-reviewed
Oui
Volume
124
Number
1
Pages
36-40
Language
english
Notes
Publication types: Journal Article - Publication Status: ppublish
Abstract
OBJECTIVE: To evaluate the dynamic properties of the horizontal vestibulo-ocular reflex (h-VOR) in the acute stage of two common labyrinthine diseases that provoke severe attacks of vertigo with spontaneous nystagmus: vestibular neuritis (vestibular loss alone) and viral labyrinthitis (cochleovestibular loss). MATERIAL AND METHODS: Sixty-three patients were investigated: 42 were diagnosed with vestibular neuritis and 21 with viral labyrinthitis. The h-VOR function was evaluated by conventional caloric and impulsive testing. A simplified model of vestibular function was used to analyze the vestibulo-ocular response to rotational stimulation. RESULTS: The results showed a significant difference in h-VOR characteristics between the two pathologies. Patients with vestibular neuritis exhibited a strong horizontal semicircular canal deficit, but no h-VOR asymmetry between the two rotational directions. In contrast, patients with viral labyrinthitis demonstrated moderate canal paresis and a marked h-VOR deficit in rotation toward the affected ear. CONCLUSION: These findings support the hypothesis that the h-VOR dynamic asymmetry that occurs after an acute unilateral inner ear lesion is not due to canal dysfunction alone, but involves complex adaptive changes in the central VOR that may implicate the otolith system. Based on histopathologic and clinical differences in the two pathologies reported in the literature, we postulate that this otolith-canal interaction is mainly linked to the loss of saccular function.
Keywords
Adolescent, Adult, Aged, Aged, 80 and over, Diagnosis, Differential, Electronystagmography, Female, Follow-Up Studies, Hearing Loss, Sudden, Humans, Kinesthesis, Labyrinthitis, Male, Middle Aged, Orientation, Otolithic Membrane, Reflex, Vestibulo-Ocular, Semicircular Canals, Vestibular Function Tests, Vestibular Nerve, Vestibular Neuronitis, Virus Diseases
Pubmed
Web of science
Create date
25/01/2008 11:00
Last modification date
20/08/2019 16:06
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