Asymmetry of voice onset time-processing in adult developmental dyslexics.

Details

Serval ID
serval:BIB_E29CDCA13EC8
Type
Article: article from journal or magazin.
Collection
Publications
Title
Asymmetry of voice onset time-processing in adult developmental dyslexics.
Journal
Clinical Neurophysiology
Author(s)
Giraud K., Trébuchon-DaFonseca A., Démonet J.F., Habib M., Liégeois-Chauvel C.
ISSN
1388-2457 (Print)
ISSN-L
1388-2457
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
119
Number
7
Pages
1652-1663
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
OBJECTIVE: The human auditory cortex codes speech temporally according to sequential acoustico-phonetic cues like the voice onset time (VOT). This coding is predominantly left-lateralized in normal readers. We examined VOT-processing asymmetries in adults with a history of developmental dyslexia (DD-history+).
METHODS: Auditory-evoked potentials (AEPs) to voiced (/ba/) and voiceless (/pa/) speech stimuli were recorded from 10 DD-history+ adults and 8 controls. Source modelling of the "release component" (RC: approximately 240 ms; time-locked to voiced consonantal release and considered reflective of VOT-processing) was conducted to explore VOT asymmetries.
RESULTS: Controls demonstrated L>R RC source probe amplitude asymmetry in the auditory cortex. DD-history+ subjects with little persistent reading deficit (n=5) demonstrated normal temporal coding but rightward asymmetry. DD-history+ subjects with severe persistent deficits (n=5) exhibited numerous supplemental AEP components (notably left hemispheric) and inconsistent asymmetry (leftward or alternating).
CONCLUSIONS: These preliminary findings suggest that DD-history+ adults process auditory speech cues differently than adults without previous DD. The nature of this processing may relate to the severity of persistent reading deficits.
SIGNIFICANCE: Previous dyslexics with little persistent deficit can exhibit atypical functional asymmetry with normal auditory temporal coding. Source modelling represents an effective, non-invasive means of exploring processing asymmetries in clinical populations.
Keywords
Acoustic Stimulation, Adult, Auditory Cortex/physiology, Cues, Data Interpretation, Statistical, Dyslexia/psychology, Electroencephalography, Evoked Potentials, Auditory/physiology, Functional Laterality/physiology, Humans, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Male, Models, Neurological, Speech Perception/physiology, Voice/physiology
Pubmed
Web of science
Create date
24/03/2013 20:01
Last modification date
20/08/2019 17:06
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