Surcharge hépatique en fer et synthèse protéique progrès apportés par les modèles expérimentaux

Details

Serval ID
serval:BIB_E107A4BA61DB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Surcharge hépatique en fer et synthèse protéique progrès apportés par les modèles expérimentaux
Journal
Annales de gastroentérologie et d'hépatologie
Author(s)
Jouanolle H., Lescoat G., Desvergne B., Deugnier Y., Brissot P., Bourel M.
ISSN
0066-2070
Publication state
Published
Issued date
10/1987
Peer-reviewed
Oui
Volume
23
Number
5
Pages
269-272
Language
french
Abstract
To understand the disturbances in protein synthesis observed during idiopathic hemochromatosis, various experimental models may be used. The aim of this research was to review the principal models employed and to demonstrate the value of hepatic tissue culture techniques in each. This method has already made it possible to explain several mechanisms involving the control of proteins in iron metabolism such as transferrin and ferritin. Tissue culture techniques of human hepatocytes should make it possible to elucidate the nature of the basic metabolic disorder in this disease responsible for the iron overload in the near future.
Keywords
Animals, Hemochromatosis, Humans, Liver, Protein Biosynthesis
Pubmed
Web of science
Create date
24/01/2008 16:26
Last modification date
20/08/2019 17:05
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