La fracture vertébrale: un facteur de risque majeur pour l'ostéoporose. [Vertebral fracture: a major risk factor for osteoporosis]

Details

Serval ID
serval:BIB_E0F92EC461B9
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
La fracture vertébrale: un facteur de risque majeur pour l'ostéoporose. [Vertebral fracture: a major risk factor for osteoporosis]
Journal
Schweizerische Rundschau fur Medizin Praxis
Author(s)
Krieg M. A., Lamy O.
ISSN
1013-2058 (Print)
Publication state
Published
Issued date
02/2004
Volume
93
Number
9
Pages
321-8
Notes
Comparative Study English Abstract Journal Article Review --- Old month value: Feb 25
Abstract
At the age of 50, a women has a lifetime risk of more than 30% to present a radiological vertebral fracture (vertebral deformity). Among the women of 50 to 79 years, 12 to 20% of them have one or more prevalent vertebral deformities. For Switzerland, it represents about 130,000 to 220,000 women. For men, the global prevalence of these fractures is the same. However, they usually happen in younger men who are exposed to greater trauma than women. The situation is more dramatic in patients hospitalised for a hip fracture, because about 3/4 of them have one or more vertebral deformities. It is important to detect these vertebral deformities because they represent a significantly higher risk to have subsequent fractures, particularly vertebral (approximately 5x), but also hip fractures (approximately 2x). This risk remains increased, whatever is the number or the grade of the deformities, although it is higher in patients with many fractures or with severe deformities. It is also important to detect vertebral deformities, because cost-effectiveness of treatments such as bisphosphonates, calcitonin, raloxifen, or PTH is the highest in patients with prevalent vertebral deformities. Unfortunately, only 1/3 of vertebral deformities are diagnosed. In consequence, it is of major importance to develop screening and diagnosis strategies for these deformities. Morphologic vertebral assessment by DXA should be an interesting approach for this purpose.
Keywords
Age Factors Aged Aged, 80 and over Bone Density Female Follow-Up Studies Hip Fractures/complications Humans Incidence Male Middle Aged Osteoporosis/*complications/diagnosis/drug therapy/epidemiology Osteoporosis, Postmenopausal/complications/diagnosis/drug therapy/epidemiology Prevalence Recurrence Risk Factors Sex Factors Spinal Fractures/epidemiology/*etiology/prevention & control Time Factors
Pubmed
Create date
25/01/2008 14:55
Last modification date
20/08/2019 17:05
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